báo cáo hóa học:" Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL-18" ppt

... 1 of 9 (page number not for citation purposes) Journal of Translational Medicine Open Access Research Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin ... subpopulations of immune cells of the adaptive and innate immune system. It activates effector T cells; induces IFN-γ, TNF-α, IL-1α, and GM-CSF producti...

Ngày tải lên: 18/06/2014, 15:20

... limitation of current in vitro and in vi vo models is that they often overlook the contribution of the ECM and the tumor microenvironment toward the initiation and progress ion of tumorigenesis. ... increased angiogenesis and tumor growth in vivo [9]. We have successfully developed an ELISA assay to detect and quantify levels of cryptic epi- tope HU177 in the serum of...

Ngày tải lên: 18/06/2014, 16:20

... 2 Correlation between serum cytokine levels in seizure patients. (A-D) Correlation between serum levels of IL-1b and HMGB1 (A), IL- 1b and IL-6 (B), IL-1b and TNF-a (C), and IL-6 and TNF-a (D) ... ± standard error of mean Choi et al. Journal of Neuroinflammation 2011, 8:135 http://www.jneuroinflammation.com/content/8/1/135 Page 4 of 9 RESEARCH Open Access Increased lev...

Ngày tải lên: 19/06/2014, 22:20

... 2 Comparison of IC50 concentrations of temozolomide when tested alone and in combination with dasatinib in HT144, Lox-IMVI, Malme-3M and Sk-Mel-28 cells. Standard deviations represent average results of ... cycle arrest. Effect of dasatinib on cell cycle arrest. Comparing the effect of dasatinib versus untreated cells on the percentage of cells tested in the G1, S and...

Ngày tải lên: 18/06/2014, 15:20

... derived progenitor cells (hemato- poetic progenitor cells, HPCs) and microvascular endothelial cells in bone marrow. Endothelial cells appear to regulate the trafficking and release of HPCs from bone marrow ... ± 0.18, and 1.71 ± 0.18 for CD34, and saline-treated vessels, Characterization of human CD34+ cellsFigure 1 Characterization of human CD34+ cells. A. Scatter anal...

Ngày tải lên: 18/06/2014, 15:20

... global changes of both gene and miR expres- sion associated with LPS and IFN-g induced DC matura- tion. Gene and miR changes in DCs were assessed aft er 4, 8 and 24 hours of LPS and IFN-g stimulation. ... 24 hours of maturation with a 37-fold and 21-fold increase respectively. The expression of the cell cycle and cell signaling genes GADD45A and RGS1 also increased m...

Ngày tải lên: 18/06/2014, 16:20

... areas of clinical concern; and 3) explore pso- riasis patients' perceptions of the impact of psoriasis. Ful- fillment of these objectives will satisfy the first component of the U.S. Food and ... open-ended and closed- ended questions. Four of the clinicians had over 10 years of experience, and one clinician had 7 years of experience. Four of the clini- cians pr...

Ngày tải lên: 18/06/2014, 18:20

... d ± 1.96*SD of d. The Bland-Altman plot of UK and US weights showed that 96.4% of the difference scores were between the limits of agreement, 3.3% below the lower agreement line, and 0.3% above ... magnitudes of correlation between the Japan weighted scores and these variables were higher than those between both UK and US weighted scores and these factors. The magnit...

Ngày tải lên: 18/06/2014, 19:20

... alterations on the biomechanics of gait of the PAD patients as revealed by the statistical comparisons performed between pre and post- treatment and between post-treatment and the healthy controls. Conclusions: ... PAD patients between pre- and post- pharmacological treat- ment (Table 3). Discussion The purpose of this study was to determine the impact of pharmacologica...

Ngày tải lên: 19/06/2014, 08:20

... the standard curve OD reached 1.0. Softmax Pro softwar e version 3.0 (Molecular Devices) was used to generate the best-fit plot of the standard curve, using the log-logit option. Calculation of ... the association between antibody concentrations to A b monomer and oligomeric Ab using pooled data from all groups and also within each group. Differences in mean antibody levels between...

Ngày tải lên: 19/06/2014, 22:20