báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx
báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx
... 1 of 14 (page number not for citation purposes) Journal of Translational Medicine Open Access Review Recent progress towards development of effective systemic chemotherapy for the treatment of ... the orthotopic RG-2 rodent malignant glioma model. Herein I discuss this novel strategy to improve the effectiveness of systemic chemotherapy for the t...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo khoa học: Affinity purification-mass spectrometry Powerful tools for the characterization of protein complexes ppt
... affinity-based methods. The common theme of these is the use of an inherent interaction (affinity) of two biomolecules. If one of the molecules is immobilized on a solid support, the interacting molecule ... and that the results are usually straightforward to interpret. The downsides are the statistical limitations imposed by the method. These include the requirement t...
Ngày tải lên: 31/03/2014, 07:20
báo cáo hóa học:" A highly invasive human glioblastoma pre-clinical model for testing therapeutics" pot
... disease. Furthermore all of the GBM lines express high levels of MCP-1, also a marker of poor prognosis in patient gliomas [26]. All of these mark- ers are consistent with the GBM nature of the GBM-M2 cells. We ... novel therapeutic interventions against vascular flow and formation. Given the resemblance of this animal model to patient GBM we proceeded with the evaluatio...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors" ppt
... have validated the oncogenic potential of TRIP-Br2. Overex- pression of TRIP-Br2 resulted in the upregulation of E2F- mediated transcription, the transformation of NIH3T3 fibroblasts and the promotion of ... interrogated to determine the in silico gene expression profiling of TRIP-Br2 across all human tissues. The NCBI symbol SERTAD2 was used in the query of the...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis" pptx
... discuss the potential use of the adi- pose derived cells for the treatment of inflammatory con- ditions in general, with specific emphasis on multiple sclerosis. Due to the chronic nature of the ... SVF based on the immunological profile, the length of disease progress allowing several interventions, and the fact that the disease naturally has periods of remi...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng on human promonocytic U937 cells" potx
... Operating Softwares (GCOS). The signal intensity of each gene was firstly normalized with the total intensity of all genes from the genechip, and then the normalized signal of each treatment was ... incubated at 37°C for 60 min and then inverted to observe the gel formation. Positive result is indicated by the formation of an intact gel which does not collapse upon inv...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
... advances the reasoning for the hypothesis that explains the CRP cycles in terms of homeostatic immune regulatory cycles. This knowledge might also open the way for improved timing of treatment( s) for ... was established, we could then plot where on the L- Timing of chemotherapy with the CRP cycle in a patient with advanced melanomaFigure 5 Timing of chemotherapy...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity" ppt
... IL-13RA1). These data offer an explanation for the variable expres- sion, rather than abolishment, of mRNA/protein of var- ious cytoki nes and chemokines in IRAK4-deficient cells. Further more, these ... names are given in the left panel and gene expression in the right panel. The relative expression of the gene in IRAK4-deficient monocytes is depicted by the colour of...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis" ppt
... to noise) of more than 3-fold. The loss of correlation between the amount of globin in the sample and the number of false d etections indicates the benefits of this approach. This improved performance ... and editing of the manuscript. SL completed the analysis of the protocol selection study, participated in the analysis of the SAHA data and participated i...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Co-morbidity and visual acuity are risk factors for health-related quality of life decline: five-month follow-up EQ-5D data of visually impaired older patients" ppt
... confined to bed. Therefore, the results of our study on QOL decline may even be an underestimation of the actual QOL decline in visually impaired older patients. Furthermore, in the field of ophthalmology ... referral to another sub-specialty may be of benefit for the health and vision-related QOL of the patient and for the involvement of ophthalmologists in their...
Ngày tải lên: 18/06/2014, 19:20