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báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc

báo cáo hóa học:

báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc

... that the DTA -H19 construct has a high therapeutic potentialand is a very promising candidate for ovarian cancer ther-apy in humans.Materials and methodsCell culture The human ovarian carcinoma ... effective anti-tumor agents. Various gene therapy strategies for the treat-ment of ovarian cancer are currently under development and aim towards maximal treatment efficacy and minimaladverse ... differentially expressed and gene expressionprofiling allows an individualized DNA-base approach to cancer therapy. The therapeutic potential of the DTA -H19 vector was tested in a rat animal tumor...
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Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx

... article as: Amit and Hochberg: Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory ... healthy mice were used as control. The total tumor area of each bladder was determined and the mean of the total areas was calculated for each group. The Mean and SD of bladder tumor area (A) and ... RESEARC H Open Access Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequencesDoron...
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báo cáo hóa học: " Development and preliminary evaluation of a quality of life measure targeted at dementia caregivers" doc

... of the paper. All authorsread and approved the final manuscript.Additional materialAcknowledgementsThis study was funded by the State of California, Department of Public Health through the ... particular to Michele Carter, RN, of UCLA, and Monica Moore, MSG, of the Alzheimer's Association California Southland Chapter. Other agencies that provided invaluable assistance include the Alzheimer's ... purposes)Health and Quality of Life OutcomesOpen AccessResearch Development and preliminary evaluation of a quality of life measure targeted at dementia caregiversBarbara G Vickrey*1, Ron D Hays2,...
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Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx

... or pair housed and cared for according to the American Association for Accreditation of LaboratoryAnimal Care guidelines. The Wyeth Institutional AnimalArai et al. Journal of Translational Medicine ... required upon hand-off for assay validation. SJ, AW, SWA and KA performed the in vitro assays on mon-keys treated with Ab-01 and control Ig and analyzed the data, and KA and SAperformed the experiments ... "inventoried" assaysavailable from ABI, and are described in Table 2. cDNAsynthesis, preparation of samples for TLDA assay andmeasurements of RNA concentration were performed asdescribed for the human...
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báo cáo hóa học: " Development and psychometric assessment of the COPD and Asthma Sleep Impact Scale (CASIS)" pdf

... respiratory disease and help to understand the impact that COPD and asthma have on outcomesrelated to sleep.AbbreviationsALIS: Asthma Life Impact Scale; ANOVA: Analysis of vari-ance; AQLQ: Asthma ... clinician-rated and patient-rated severity, overall health, and exacerbation status for patients with asthma. The ability of the CASIS to differen-tiate by disease severity and overall health status ... (IRT)analysis examined item performance [19,20]. After the final CASIS items were determined then the reliability andvalidity of the measure was evaluated [21]. All data analy-ses were performed...
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báo cáo hóa học:

báo cáo hóa học: " Development of a self-reporting tool to obtain a " docx

... othercomorbidities, and the utilization of health care andnon-health care resour ces, laboral status and a stimatedcost of the fibromyalgia impact during the year before.An eva luation was also made of patient ... CLINISAS, Madrid), I Vallejo (HospitalClinic, Barcelona), J Vidal (Hospital General, Guadalajara). Milena Gobbo andUnidad de Investigación de la Fundación Española de Reumatolog a, for their ... intrinsica lly evaluates the emotional aspects:anxiety and depression, and their impact upon socialaspects. It also evaluates patient functional capacity,fatigue, sleep quality, pain, a nd the way...
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báo cáo hóa học: " Development and validation of the Treatment Related Impact Measure of Weight (TRIM-Weight)" pdf

... properties of both the total as w ell as domain subscale scores and the data from the validation study supports the claims for reliability and validity for both. As a result, eachdomain subscale can ... believe the bias introduced by a web-based study to be minimal, given the preva-lence of computer access now available in the U.S., U.K.,Canada and Australia. Also potentially biasing was the self-reported ... analysis and interpretation and manuscript preparation. DMB was the main contributor to the data analysis and interpretation and contributed to the manuscript preparation. All authors read and approved...
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báo cáo hóa học:

báo cáo hóa học: " Development of the Knee Quality of Life (KQoL-26) 26-item questionnaire: data quality, reliability, validity and responsiveness" pptx

... sample sizeneeded for purposes of evaluation. The denominator was the standard deviation of the score changes for thosepatients in the test-retest analysis.Health and Quality of Life Outcomes ... to as the KQoL-26, are computed by summing the items where half or more are completed for the relevantscale and transforming to a 0–100 scale. The scores wereapproximately normal on a scale of ... symptoms and change of job. The results arestatistically significant for 26 of the 30 tests. The samplesizes are relatively small for those patients who havechanged or are considering changing their...
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báo cáo hóa học: " Development and validation of a preference based measure derived from the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for use in cost utility analyses" doc

... was undertaken using the timetrade-off (TTO) technique where individuals are asked toundertake conventional TTO valuations for a sample of health states. The Measurement and Valuation of Health(MVH) ... exercise. *DM ran the analysis to identify items for the valuation exercise,analysed the validation data and contributed to the writ-ing of the manuscript. JB designed and managed the valu-ation survey, ... respectively.Table 5 presents examples comparing the predicted valuesaccording to each model and the actual values for eachhealth state.Validation of the preference based CAMPHOR scale A majority...
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báo cáo hóa học:

báo cáo hóa học: " Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL" pot

... of the study, collected the data and performed the statisticalanalysis BD and VM: participated in the design of the study, collected medical data and participated to the inter-pretation of data ... consist-encies.Construct validity- Factor analysis The factor analysis with varimax rotation identified a structure of five factors, which accounts for 46.3% of the total variance (Table 4). The content of each dimensionwas ... phases. The study was approved by the local medical ethics committee. All patients gaveinformed consent to participate. The procedure for data collection For each phase, the procedure of data...
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