... tumour-associated antigens and
thereby, represent a major obstacle to immunotherapy.
Thus, reducing their number or inhibiting their effector
functions intuitively has the potential of increasing the
efficacy ... and man toward delineating, e.g.,
the relative effects of T cells and depletion of Tregs. In the
process, the paper by Rasku et al. [5] exemplifies the jour-
ney...
... of ART in perina tal
HIV-infection.
With congratulations to Hye-Won Chung [3] and to
Raffaele Badolato and their respective co-workers, the
3rd “Excellence in Translational Medicine” and 2nd
“Bedside-to-Bench” ... inhibiting several viruses, including HIV.
With the foregoing in perspective, the study by
Badolato et al. [4] provides an exemplarly example of
translational...
... differ in how much they use the prosthesis and in the
type of activities they can perform with their prosthesis
[7].
Walking ability with a prosthesis depends on several fac-
tors including patient's ... between the LCI and the TUG test
and between the LCI and the EQ-5D. The reliability tests
showed good internal consistency and the test-retest reli-
ability...
... perform the Ash-
worth test as he would perform as usual in the clinic.
Total time to perform the Ashworth test including posi-
tioning and instructing of the patient was about 5 min-
utes. The instrumented ... understanding energy dissipation
in functional tasks, e.g. during walking.
Clinical implications
The current findings that joint viscosity and reflex tor-
que depen...
... used
to grind the tissue to a pulp. 200 μl of GT Buffer was
added into the tube and the sample tissue was continu-
ally homogenized with grinding. 20 μlofProteinaseK
(10 mg/ml) was added to the sample ... previous step
(including any precipitate) was applied to the GD col-
umn, and was centrifuged at 13,000 rpm for 2 minutes.
The Collection Tube containing the flow-through w...
... at the initial contact (KIC index), both PWS
and DS obtained values close to normal in midstance
(KmSt index). In the swing phase, the maximum value of
knee flexion (KMSw index) was reduced in ... at the Initial Contact
(IC);
- the values of maximal ankle dorsiflexion during stance
phase (AMSt index) and the maximal flexion of the knee
(KMSw index) during swing phase;...
... important step in understanding the
human-machine interface.
By manipulating feedforward and feedback uncertainty
we have shown that the seemingly trivial task of grasp-
ing and lifting objects ... people act in anticipation of
their actions in the absence of ext ernally-a rising cues.
The formation and maintenance of internal models has
been studied in healthy individua...
... data and writing the manuscript, RLH participated
in interpreting data and writing the manuscript, and
MMM designed the study, supervised data collection and
analysis, and participated in interpreting ... that they have no competing interests.
Authors' contributions
LA participated in performing the experiments, interpret-
ing data and writing the paper. WZR p...
... sub-
jects in constrained functional tasks, i.e. when the start/
end point of the hand, and the sequence of events within
the task, are both fixed and the object is picked up from
and returned ... that, focusing on the characteristics of the move-
ment itself rather than the outcome of the movement (e.g.
end point accuracy in a pointing task), is of most benefit
i...
... the points A or C, and the values of the distance at
the points A, C are greater than the values of the distance at the points E, H, I, we get the desired
strict inequality and this part of the ... negative at the left-hand
side of α
∗
and positive at the right-hand side of α
∗
.
There are three different cases regarding the position of the point N
(the inte...