báo cáo hóa học:" Summary of the primer on tumor immunology and the biological therapy of cancer" ppt
báo cáo hóa học:" Summary of the primer on tumor immunology and the biological therapy of cancer" ppt
... signaling processes. The ligation of VEGFR-2 by the majority of VEGF isoforms triggers the proliferation, migration and survival of endothelial cells, which in tumors form the framework of immature new ... Ab alone or in combination with other modalities to treat murine tumors. Activation of vas- culature in tumors, extravasation and proliferation of T cells, and inc...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo sinh học: "The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program" doc
... science, development and application of biological therapy and immunotherapy. The society and its educational programs have become premier destinations for interaction and innovation in the cancer biologics ... Primer on Tumor Immunol- ogy and Biological Therap y of Cancer™ provided a comprehensive overview of the principles of immunol- ogy, with the aim...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection" potx
... HIV infection and autoimmune diseases. The depletion of the CD4 T lymphocytes is the hallmark of the progression of HIV infection and, in the absence of antiviral treatment, the main contributor to the ... docking into a conserved hydro- phobic pocket, a discontinuous region at the interface between the inner and the outer domain of gp120 [52]. On the ot...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot
... also performed to find the appropriate serum dilution able to saturate alternatively one of the two CaSki antigens, and determine the relative contribution of each immunogen. The sera of the E6- and E7-immunised ... infection and the appearance of cervi- cal intra-epithelial neoplasias, the long-term durability of the protection by these vaccines has not yet be...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases" pdf
... modification in the HI loop and mutation of the fiber shaft KKTK domain to GATK (the HSPG binding ablation) showed reduced liver and spleen trans- duction in compari son with wild type virus. This demonstrates ... MR images was done by JH and SLA and quantification of tumor volumes and subsequent analysis of the data by SLA. Statistical calculations were performed by...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers"" docx
... approaches to the validation of known immune response biomarkers and the standardization of the respective assays to enhance the likelihood of obtaining informative returns from ongoing immunotherapy ... institutions. This working group will focus primarily on the standardization and corroboration of commonly utilized assays for meas- urement of host -tumor interact...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma" ppt
... results. The apoptotic effect of the sigma-2 ligand, SV119, is enhanced by conventional chemotherapy in vitroFigure 2 The apoptotic effect of the sigma-2 ligand, SV119, is enhanced by conventional ... the sigma-2 ligand, SV119, is enhanced by conventional chemotherapy in vivoFigure 4 The pro-apoptotic activity of the sigma-2 ligand, SV119, is enhanced by conventional che...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson''''s disease" doc
... sepa- rated and cultured by QG. DY, LL and SC gave advises on the work and helped in the interpretation of the data. WL supervised all the work and wrote the paper together with MM. All authors read and ... rotenone. (D) The number of TH-ir neurons in the cultures treated with fresh medium only (Control), with fresh medium in the presence of 25 nM rotenone...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity" ppt
... presentation. DJD, ST and BBF provided advice on the conception and design of the clinical and animal experiments. DPS and REWH were imperative to the conception, design and implementation of the experiments ... functions such as cellul ar recruitment, despite the severe impairment of the expression of other family members. As demonstrated here, the expressio...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy" pot
... as the first line chemotherapy. The results showed that the expres- sion level of polh in tumor cell lines was correlated with the sensitivity of oxaliplatin (Figure 2). For the tumor tissue, the ... expression only occurred in 28.75% cases (23 out of 80), and the expression was modest. However, strong correlation was found between polh expression and treatment res...
Ngày tải lên: 18/06/2014, 16:20