báo cáo hóa học:" Validation of a flow cytometry based chemokine internalization assay for use in evaluating the pharmacodynamic response to a receptor antagonist" potx

... flow cytometry- based pharmacodynamic assays. Here we report the validation of a flow cytometry- based chemokine internalization assay for use in evaluating the effect of a receptor antagonist in ... foundation in which to base the validation of a flow cytometry pharmacodynamic assay and applying the "appropriate" par...

Ngày tải lên: 18/06/2014, 15:20

... study aimed to evaluate the capacity of a static platelet adhesion assay to detect platelet inhibiting effects of ASA and clopidogrel. The adhesion assay measures several aspects of platelet adhesion simultaneously, ... section). A special case was observed for Factor 8. Pairwise analysis of the data regarding adhesion to collagen in the presence of Mg 2+...

Ngày tải lên: 18/06/2014, 15:20

... tested in multiple assays on more than one day. For example, fac- tors that contribute to inter assay variability for the tetramer assay include cell preparation, staining methods, machine setting, ... Furthermore, the validation of immu- noassays was identified as one of the critical areas for improvement when using these assays to evaluate immune responses in...

Ngày tải lên: 18/06/2014, 15:20

... data, and contributed to the man- uscript. All authors have read and approved the final manuscript Acknowledgements The authors would like to acknowledge the Department of Family Medicine and ... studied, and the linguistic and health value orientations of the population sampled. Finally, and perhaps most importantly, there are no gold stand- ards for identifying, class...

Ngày tải lên: 18/06/2014, 19:20

... statisti- cal software (version 16.0) (SPSS Inc., Chicago) was used for data analysis and the significant level was set up at p < 0.05. An intra-class correlation (ICC) approach was used to examine the ... treatment response and their HRQoL. HFS is common in Asian countries, and valida- tion of a Chinese version of HRQoL scale will be useful in clinical practice among...

Ngày tải lên: 18/06/2014, 19:20

... s- rand, the Ugandan National Coun cil for Science and Technology, Hospice Africa Uganda and the Hospice Palliative Care Association of South Africa. The APCA African POS The APCA African POS contains ... reviewed the paper. TM served as Principal Investigator at one of the participating sites, managed the research nurse and reviewed the paper. LMS was Principal Investig...

Ngày tải lên: 18/06/2014, 19:20

... ECOHIS and collaborating with us in the validation of the French version of the scale. In addition, the authors would like to acknowledge the financial support of the Canadian Institutes of Health ... impact increasing by age. In examining the internal consistency of the French ECO- HIS, using data from the community -based sample, we found Cronbach&apo...

Ngày tải lên: 18/06/2014, 22:20

... data analysis and helped to draft the manuscript. MT partici- pated in data analysis and performed the statistical analy- sis. AM participated in the design of the study and data analysis. GA ... induce a facilitation of walking in PD subjects, due to the bypass of the affected neural pathways, i.e. the basal ganglia. In fact, it has been shown that basal gan...

Ngày tải lên: 19/06/2014, 10:20

... is the use of a 7- item modified Morisky scale for the validation of TSQM- 9. An item from the original Morisky scale related to stop- ping medication because of feeling worse with the medi- cation ... to the behaviors of health care providers and patients alike. Conclusion The IVRS-administered TSQM-9 was found to be a reliable and valid measure to asses...

Ngày tải lên: 18/06/2014, 18:20

... employee of AstraZeneca. Authors' contributions All authors were involved in data interpretation and man- uscript preparation. Data analysis was provided by Astra- Zeneca. All authors read and approved ... Cooper A, Karagiannis D, Hatlebakk J, Agréus L, Jab- lonowski H, Zapardiel J: Impact of gastroesophageal reflux dis- ease on patients' daily lives: a European observation...

Ngày tải lên: 18/06/2014, 19:20