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báo cáo hóa học:" Adjuvant therapy of melanoma with interferon: lessons of the past decade" pot

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báo cáo hóa học:" Adjuvant therapy of melanoma with interferon: lessons of the past decade" pot

... CentralPage 1 of 11(page number not for citation purposes)Journal of Translational MedicineOpen AccessReview Adjuvant therapy of melanoma with interferon: lessons of the past decadePaolo ... in the blood of melanoma patients during the four weeks of HDI IV induction therapyFigure 1A-B-C. Levels of circulating Treg cells (CD4+CD25+FoxP3+) in the blood of melanoma patients during the ... Adjuvant therapy of malignant melanoma and the role of sentinel node mapping. Recent Results Cancer Res2000, 157:178-89.11. Kimyai-Asadi A, Usman A: The use of interferon alfa as adjuvant therapy...
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Báo cáo hóa học: "Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy" pdf

... suggest that the detection of these two phenotypes might help the selection of patients enrolled invirally-mediated gene therapy trials.Background The incidence and mortality of pancreatic ... consisting in the induction of type I IFNs followed by the transcriptionalactivation of hundreds of IFN-stimulated genes (ISGs)[12]. In turn, the activation of ISGs promotes the rapidexpression of proteins ... predictresponsiveness of brea st cancer to chemotherapy andradiation therapy based on the expression pattern of ISGs.In this study, we identified by transcriptional profilingtwo ISG-defined phenotypes of panc...
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báo cáo hóa học:" Main roads to melanoma" potx

... malignant melanoma. The reten-tion of MITF expression in the vast majority of human pri-mary melanomas, including non-pigmented tumors, isconsistent with this hypothesis and has also led to the widespread ... [157,158]. These observations areconsistent with the hypothesis that this pathway contrib-utes to behavior of melanoma cells and might be inappro-priately deregulated for the development of the disease.In ... the total number of nevi and the presence of dysplastic neviwere associated with a higher risk of melanoma, Sunexposure and a history of sunburn is associated with melanoma risk in melanoma- prone...
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báo cáo hóa học:" Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection" potx

... features of both HIVinfection and autoimmune diseases. The depletion of the CD4 T lymphocytes is the hallmark of the progression of HIV infection and, in the absence of antiviral treatment, the main ... distinctmonoclonals, two of them preventing, the third one accel-erating the development of the disease [40]. The effect of each reagent on the signaling activated by CD4 via the p56lck interacting ... created upon the interactions of CD4 with gp120, with monoclonal antibodies, or other ligands. The binding of gp120 to CD4 involves a well-defined sitewithin the first Ig-like domain of CD4 (CD4...
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Báo cáo hóa học: " Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction" ppt

... based on the expression of the cytosolicenzyme aldehyde dehydrogenase ( ALDH) [ 6], although the relative contributions of the different sub-popula-tions and consequently their relative therapeutic ... Stratifying the mice based on the day 0 infarct size in the presentstudy did not, however, influence the interpretation of the data and all transplanted animals were included in the final evaluation.NOD/SCID ... densityWe analyzed whether the transplanted cells promotedre-vascularization of the infarcted tissue by hostendothelial cells. Sections were stained with a murine-specific CD31 endothelial antibody...
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Báo cáo hóa học: " Oxidative stress in NSC-741909-induced apoptosis of cancer cells" potx

... obtained with cells that were treated with the lead compound, oncrasin-1 (data not shown). Wethen evaluated the generation of ROS as a function of NSC-741909 concentration 6 h after treatment with NSC-741909. ... wasdetermined by using the SRB assay. To test for the genera-tion of ROS, the cells were treated with 1 μM NSC-741909 for 6 h and then stained with H2DCF-DA, asdescribed earlier. The results showed ... cells, we hypothesized that reactive oxygen species (ROS) may be involved in the suppression of JNK dephosphorylation and the cytotoxicity of NSC-741909.Methods: The generation of ROS was measured...
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Báo cáo hóa học: " Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice" doc

... injection of Ad5IL-12 vector can enhanceprostate cancer therapeutic efficacy versus that of vector therapy alone. The inclusion of RU486 may furtherenhance tumor immunity within the TSLN through ... indication for the inclusion of RU486 in therapy. Thus, the use of RU486 in prostatecancer therapy could have effects on cachexia, andro-gen-dependent tumor growth and as an adjuvant inimmune ... protecting against the spread of tumor cells into the draining TSLN. While most of the anti-tumor effect is clearly the result of the proinflam-matory response induced by the Ad5IL-12 vector,...
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báo cáo hóa học: " Body mass index and health related quality of life in elementary school children: a pilot study" pdf

... healthstatus. On the other hand, a health status profile providesa multidimensional evaluation of all aspects of health.Health profiles are popular in situations where the inter-action of the physical, ... score was 52.1 with rangefrom 6.3 to 56.7. Table 1 depicts the frequency of students with physical summary scores in each category basedupon their BMI classification. The percentage of childrenreporting ... Since the study was conducted prior to the recommendation, the traditional classification on BMIwas used in this study so the findings are consistent with the previous records.Based on the 2007...
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báo cáo hóa học: " Struggles, strengths, and strategies: an ethnographic study exploring the experiences of adolescents living with an ostomy" doc

... hospital with me. She stayed over with me at the hospital Andwhile it is nice to have someone with you at all times,she was there on (a special day) with me, yet the otherkids were at home without ... illness in the family it takes away from a lot of the other siblings, and they also need care."Participants sometimes appeared to blame themselves fortheir parents' lack of time for ... care for the adolescent with the ostomy andj-pouch. As an example, a participant described the role of her friends during times of recreation."I even go swimming with my friends and they basi-cally...
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Báo cáo hóa học: " Associations between disease severity, coping and dimensions of health-related quality of life in patients admitted for elective coronary angiography – a cross sectional study" pdf

... procedures. The presence of CAD was defined as a ste-nosis of at least 50% of the vessel lumen diameter in any of the main coronary arteries or their major side branches.A modified version of the Wilson ... majority (81%) of the patients, andwas significantly more frequent in men. The mean value of the LVEF was 64.6 (12.0), and 12% of the participantshad LVEF below 50%. A majority (82%) of the partici-pants ... coping. The first is aimed at changing the situation causing the distressand to relieve the perceived problem, while the second isaimed at changing the emotions caused by the stressfulevent. We therefore...
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