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báo cáo hóa học:" Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells" pptx

báo cáo hóa học:

báo cáo hóa học:" Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells" pptx

... shown). LXR agonists induce gene expression in rodent peripheral blood cells in vivoTo determine whether the presence of LXR and LXR in peripheral blood cells would result in regulation of geneexpression, ... express LXR and LXR , and respond to LXR agonisttreatment by time- and dose-dependently inducing LXR target genes. Transcript levels of LXR target genes in peripheral blood are relevant and useful ... of 15(page number not for citation purposes)Journal of Translational MedicineOpen AccessResearch Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral...
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báo cáo hóa học:" Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment" pot

... were isolated for hematoxylin and eosin staining or anti-insulin immuohistaining. A, Representative morphology of pancreatic islets. a-f: hematoxylin and eosin staining. Arrow showed the islets' ... glucose-induced ROS production in vitro, RIN-m cells were incubated in the presence of highconcentrations of glucose, and the production of ROS wasmeasured. Exposure of RIN-m cells to increasing ... activation induced by IL-1β and IFN-γ was investigated.Results: In alloxan-induced diabetic mouse model, AL-1 lowered blood glucose, increased insulin and prevented loss of beta cells and their...
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báo cáo hóa học: " Feasibility and acceptance of electronic quality of life assessment in general practice: an implementation study" pdf

... enrolment and obtaining informed consent,2. an explanation of the handling of the QL-recorderto participating patients,3. interpretation and use of results during the consul-tation.Training sessions ... physicians in handling the electronicequipment and interpreting HRQoL scores, and in effi-cient provision of instructions and information topatients, (iii) continued analysis of any barriers affectingthe ... with-drew informed consent after initially having indicatedinterest in participation. Reasons for withdrawal includedlack of time, change in practice software and severe illness of the practice...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "DESIGN AND IMPLEMENTATION OF A LLXICAL DATA BASE " docx

... necessarily incomplete overview of the organization of the lexicon and the role of morphology in theoretical and computational linguistics has emphasized two basic types of requirements: the linguistic ... system usin B indexed sequential and direct access files. In its present implementation, on a VAX-750, words and morphosyntactic elements are stored in indexed sequential files, lexemes in direct ... question of the relation between lexicon and morphology from the point of view of both theoretical linguistics and computational linguistics. Section 2 discusses the relational word-based model of...
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Báo cáo khoa học: Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii Implications for the disulfide metabolism of anaerobic hyperthermophiles doc

Báo cáo khoa học: Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii Implications for the disulfide metabolism of anaerobic hyperthermophiles doc

... forCoA in maintaining a reducing environment or servingas a pool of reducing equivalents at the very high tem-peratures and high concentrations of metals found in the natural environment of Pyrococcus. ... flavinisoalloxazine ring with the C4 position of the nicotina-mide ring located 3.49 A˚from N5 of the isoalloxazinering. The active site cysteine thiolate is 3.48 A˚fromN5 on the si-side of the flavin, ... disadvantage.Physiological role of CoADR and NAD(P)H in PyrococcusThe maintenance of low intracellular levels of cysteine in organisms has been attributed to the avoidance of the hydrogen peroxide produced during the...
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báo cáo hóa học:"Necessary and sufficient condition for the smoothness of intersection local time of subfractional Brownian motions" docx

... proof of Theorem 2. 4. Smoothness of the intersection local time In this section, we consider the smoothness of the intersection localtime. Our main object is to explain and prove the following ... below).For information about publishing your research in Journal of Inequalities and Applications go tohttp://www.journalofinequalitiesandapplications.com/authors/instructions/For information ... Existence of the intersection local timeThe aim of this section is to prove the existence of the intersectionlocal time of SH and SH, for an H =12 and d ≥ 2. We have obtainedthe following...
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báo cáo hóa học:

báo cáo hóa học:" MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells" doc

... expression profiles of miRNAs and transcripts using three hES cell lines, embryonic bod-ies (EB) produced from one of the cell lines and five types of terminally differentiated adult cells. The integration ... H9 and BG01v are names of hES cells lines. P denotes the number of passages of the cell lines. H9-EB denotes embryoid body (EB) prepared from cell line H9 and the day indicates the time in ... NODAL, and ACVR2B [32-35].The node containing genes upregulated in EB (node C)included the genes HAND1, HOXA1, HOXB2, MSX1,MSX2, MEIS1, FGF9 and FREM1 which are involved in morphogenesis and...
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báo cáo hóa học:

báo cáo hóa học:" Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a" pot

... ResponseIntegrin SignalingVEGF SignalingFcγ Receptor-mediated Phagocytosis in MPsNeurotrophin/TRK Signalingp53 SignalingPTEN SignalingIL-6 SignalingPI3K/AKT SignalingErythropoietin SignalingClatrin-mediated ... disruption of the interaction of VCAM-1 and very late antigen -4 (VLA-4) expressed by HPCsresuling in the release of HPCs. The levels of peripheral blood CD34+ cells are also increased in PV patients ... that the increasedexpression of CCR1 and CCL3 may contribute to the pro-inflammatory profile of MPD neutrophils.Changes in serum protein levels and neutrophil antigenexpression in PV and ET...
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báo cáo hóa học:

báo cáo hóa học:" Isolation and culture of fibroblasts from endoscopic duodenal biopsies of celiac patients" pdf

... Policlinico, Mangiagalli e Regina Elena, Milan, Italy and 5Cardiothoracic Department, Institute of Cardiovascular Medicine, Center of Clinical Physiology and Hypertension, Laboratory of Clinical ... pivotal in inflammation and tissue remodellingprocess and for these reasons they are involved in the pathogenesis of autoimmune disorders suchas celiac disease. Investigations to define the role of ... growth indexes of cell cul-tures.Immunocytochemistry was positive for FSP and negativefor cytokeratin 20 in all the cultured and examined cells(Figure 3).Q-banding analysis of FBs from CD and...
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báo cáo hóa học:

báo cáo hóa học:" Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance" docx

... Clark EA,Weiss A: Differential expression of ZAP-70 and Syk proteintyrosine kinases, and the role of this family of protein tyro-sine kinases in TCR signaling. J Immunol 1994, 152:4758-4766.113. ... with a poorclinical outcome in CLL [2-8]. In the present review, the main factors playing a role in defining the biological features of CLL cells, hence eventu-ally influencing the clinical aggressiveness ... of T lymphocytes and other cells, and introduces point mutations in variable regions of rear-ranged immunoglobulin heavy and light chains [66].Another process physiologically occurring during...
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