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báo cáo hóa học:"Necessary and sufficient condition for the smoothness of intersection local time of subfractional Brownian motions" docx

Báo cáo y học:

Báo cáo y học: "Surgical and medical emergencies on board European aircraft: a retrospective study of 10189 cases"

... whichincluded the frequency and type of emergency. The frequency of aircraft diversion was also investigated. All data regardingnames, ages and the sex of the patient and the name of the air-line ... in the data analysis, literature search,revision of the bibliography, the revision and editing of most of the manuscript. BM participated in the data analysis, the revi-sion and editing of ... participated in the study design, data analysis and inter-pretation of the data as well as the writing of the manuscript.FGB participated in the data analysis and interpretation of the study. DS...
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Báo cáo y học:

Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"

... was used at a concentration of 10μM for the indicated times. The PKA activator, forskolin (Sigma) was used at a concentration of 5 μM for the indicated times. Immunofluorescenct confocal microscopy. ... ratio of 1:200, and the lysate and antibody were incubated with gentle rocking overnight at 4°C. Protein A/G agarose was then added for 6h, after which time the lysate was removed, and the ... were serum starved for 16h, and 2 X 105 cells were seeded onto the filters. The total volume on the top of the filter was adjusted to 800μL of serum free medium and 800μL of medium containing...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

... basis for structure-activity studies. The highselectivity of the a-conotoxins, together with the possibility of obtaining detailed information on their three dimen-sional structures and the relative ... domain of each subunit contri-butes to the formation of the hydrophilic pore. ACh binding proteinhas structural and functional homology to the extracellular ligandbinding domain of the nAChR, and ... structures and the relative ease of synthesis, makesthem particularly useful templates for the design of optimized synthetic peptides for the subtype characteriza-tion of nAChRs.AcknowledgementsA....
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Syntactic and Semantic Kernels for Short Text Pair Categorization" docx

... b;0 otherwise.(3)where s1a and s2b indicate the concatenation of the sequences s and t with the argument nodes, a and b, respectively and σ(h(a),h(b)) is 1 if the children of a and b are ... P2 and sum the obtained contri-bution, where P1 and P2are the set of PASs of the first and second answer3. Although different ker-nels can be used for questions and for answers, weused (and ... φu(s)=PI:u=s[I]λd(I) for some λ ≤ 1. These functions count the num-ber of occurrences of u in the string s and assignthem a weight λd(I)proportional to their lengths.Hence, the inner product of the feature...
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Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf

Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf

... knowledge of the structural and functionalproperties of IBs drawn researchers’ attention to the possibility to control the conformation of aggregatedproteins, paving the way for the use of IBs ... increased synthesis rates of DnaK,GroEL chaperones and Lon (the main heat-shock pro-tease) have been found to last for the whole length of overproduction. The extent and kinetics of the heat-shock-like ... intramolecular and intermolecular b-sheets. The use of this spectroscopictechnique for the study of IB aggregates is oftenlimited by the intrinsic insolubility of the samples,responsible for a high...
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Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

... absence of tunicamycin. Drugtreatments resulted in the accumulation of forms of the mutant proteins that were of lower apparentmolecular mass and of similar size to the unglycosy-lated form of the ... mutantforms of HFE and incubated the cells in the presence and absence of tunicamycin. Drug treatment resultedin the accumulation of an unglycosylated lower molec-ular mass form of the wild-type ... each of the substrate asparagine residues can occur independently of the glycosylation status at the other two sites.ABFig. 6. ER localization of the HFE-triple mutant and interaction of N-glycosylation...
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Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx

Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx

... nitrogen and main and side-chain oxygen atoms of Ala59 and Glu61 of one subunit and with the main chain nitro-gen of Asn114¢ of the other subunit. The contacts of the ribityl chain to His89 and Lys138¢ ... decades, the chemical nature of the second LS substrate, the four-carbon precursor of the pyrazine ring, remained unknown for a long time. The elucidation of the structure of this compound byVolk and ... to the periphery of the act-ive site is restricted by the position of Arg128 fromone side and the conformation of the loop connectingb4 with a3 (residues 85–88) from the other side. Inthe...
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Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf

Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf

... excluded. Application of procheck [76] revealed that the stereochemical quality of the model was reliable, with 84% of the residues in the most favored regions of the tetramer model and none indisallowed ... strands b2 and b6 of neighboring monomers. The p26 modifications examined in this study are notlocated in either of these strands and they are not con-sidered further.As the basic p26 oligomer ... to form tetramers, the next level of struc-ture. Modeling indicates that tetramer formationdepends upon contact of b-strand 10 from the C-ter-minal extensions of monomers A and D withb-strands...
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Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... terminal end and C2defines the domain closest to the cell membrane. Acomparison of the inferred amino acid sequence of the C1 and C2 domains reveals that only the approximatespacing of the 10 cysteine ... Lophochotrozoans, the third major group of bilateriananimals, have remained in the background of the molecular survey of metazoan development. We report the cloning and functional study of the central part of ... each of the two novel receptor genes were sequenced and the intron–exon structures of the genes determined by compar-ing the genomic sequence with the cDNA sequence.Quantification of Cg -BMPR1 and...
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Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt

Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt

... Introduction of the point mutation, and absence of unintended mutations were confirmed by DNAsequencing. The expression and purification of the mutantenzyme was performed by the same procedure as that of ... is the initial velocity of the reaction, Vmaxis the maximum velocity, [S] is the concentration of citrate, Ksis the dissociation constant of the enzyme-citrate (ES) com-plex, and a, b, and ... phosphorylationbetween the AclAB complex (holoenzyme) and the AclAsubunit alone (Fig. 6). We then followed the phosphoryla-tion levels of the AclAB complex and AclA subunit atvarious time intervals. The phosphorylation...
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