... Akira S -like receptor 4 (TLR4 )-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the LPS Journal Immunology, 162, pp. ... qua thụ thể TLR4 ”. II. Mục tiêu đề tài c chu ngi cu trong t th TLR4 ....
Ngày tải lên: 10/02/2014, 20:20
Báo cáo khoa học: Human lactoferrin activates NF-jB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling potx
... congenic TLR4 ) ⁄ ) C.C3 -Tlr4 lps-d mice. In contrast to our results, they showed that bLF-stimulated IjB degradation was rather enhanced in TLR4 ) ⁄ ) macrophages, suggesting that TLR4 is not ... pathway. TRIF-dependent NF-jB activation proceeds down- stream of TLR3 or TLR4 . However, TLR3 -triggered signaling is independent of MyD88, whereas TLR4 activates both MyD88-dependent a...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Lipopeptide structure determines TLR2 dependent cell activation level potx
... LP, CD14, TLR2 and TLR1 [15–17] and subsequent TLR2 signalling. Among the TLR2 -dependent bacterial ligands, LP are primary candidates for analysing the structural requirements for TLR2 activation. ... the huTLR2 or muTLR2 were selected as a cellular test system. These cells express both TLR1 and TLR6 . At first it should be noted that all bioactive LP used in our study were found to be...
Ngày tải lên: 30/03/2014, 11:20