analysis and determination of the stress intensity factor of load-carrying cruciform fillet welded joints
Tài liệu TREES OF THE NORTHERN UNITED STATES THEIR STUDY, DESCRIPTION AND DETERMINATION FOR THE USE OF SCHOOLS AND PRIVATE STUDENTS doc
... pollen.[Pg 25] The last of the four kinds of parts is found in the center of the flower, and is called the pistil. It is this part which forms the fruit and incloses the seed. The stamens and the pistil ... other time of the year. The plan of branching, the position, number, size, form, color, and surface of buds, as well as the arrangement of...
Ngày tải lên: 13/02/2014, 12:20
Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
... all the SMAD proteins of the HTFN and APC and b-catenin-related factors. Groups C and D involve smaller functional sets. Group C contains the Rel family and CRE binding factors involved in the ... functions, and topologi- cal features retain functionality and phylogeny. How- ever, the nature of the connections between these factors needs to be understood at the l...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf
... (Met1)-ONC (M23L) by the addition of AAP, as described in the Materials and methods. Completion of the hydrolysis was confirmed by the disappearance of the (Met1)-ONC (M23L) signal in the MALDI-TOF mass spectra ... analyzed by MALDI-TOF MS. The addition of the protease is considered the zero time point. The relative intensities of the peaks from the mass spe...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx
... more than 50% of the GlnK–TnrA interaction in the presence of 2 mm ATP. On the other hand, 2-oxoglutarate did not influence the GlnK–TnrA interaction, either alone, in the absence of divalent metals, ... affect the binding of ATP to GlnK [12]. Therefore, we investigated the binding of TnrA to GlnK in the presence of different mixtures of Mg 2+ or Mn 2+ with the...
Ngày tải lên: 06/03/2014, 00:21
Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... region of the 1 H, 15 N-HSQC spectrum of the C-terminal domain of human eRF1 illustrating the presence of two conformational states of the protein. Fig. S2. Plot of the number and distribution of the NOEs ... supported by the existence of strong cros- speaks between the signal of the HN of Gly337 in the open conformer and the signal of the wat...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Investigation of the substrate specificity of a b-glycosidase from Spodoptera frugiperda using site-directed mutagenesis and bioenergetics analysis pdf
... enzyme active sites and groups of the reactant transition state (S à )[2] ;the strength of the n oncovalent interaction between enzyme active sites and S à determines the stability of the enzyme– transition ... state (ES à ) complex and the rate of the reaction. Thus, in theory, modifications of the enzymatic specificity could be accomplished by changing a ctive-s...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot
... [36,37]. Furthermore, the analysis of the calculated structures revealed a short distances between NH of Leu7 and the side chain carboxyl group of the Asp6 residue (< 0.28 nm), and NH of Leu7 ... isomerism. Characterization of the secondary structure of these two ligands of ODN receptors should provide useful information for the design of potent, stable a...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: Analysis of the CK2-dependent phosphorylation of serine 13 in Cdc37 using a phospho-specific antibody and phospho-affinity gel electrophoresis doc
... phosphoryla- tion is one of the major mechanisms used to control the function, localization and stability of proteins inside cells [1]. Therefore, the analysis of protein kinase activity and the phosphorylation ... when incubated with either CK2a or CK2 holoenzyme in the presence of ATP and Mg 2+ (lanes 6 and 9). The absence of either CK2 (lane 3), Mg 2+ (lanes...
Ngày tải lên: 30/03/2014, 03:20
Báo cáo khoa học: The C-terminal region of CHD3/ZFH interacts with the CIDD region of the Ets transcription factor ERM and represses transcription of the human presenilin 1 gene pot
... Control of the level of presenilins and its coordination with other components of the c-secretase complex are likely to be tightly regulated and we studied the transcriptional control of the PS1 ... activity, indicating the crucial importance of these two Ets motifs [15]. In addition to controlling the level of gene expression, Ets factors may direct the choice...
Ngày tải lên: 30/03/2014, 09:20
Báo cáo khoa học: Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395 docx
... report the effects of these mutations on the thermodynamic properties of the FAD and also their consequences on the kinetics of FAD reduction. The thermodynamic properties of the wild-type and mutant ... flavin cofactors, and also of the haems in the case of NOS and P450 BM3. In spectroelectrochemical titrations of the isolated domains, the lack of o...
Ngày tải lên: 30/03/2014, 14:20