... to examine the interactions between DoD and FDA as they affect the development and acquisition of drugs and biologics for CBW defense and (2) to identify potential improvements in those interactions ... xv drug and biologics development because of the increased apprecia- tion of the threat of biological weapons. The CBW threat, both to national and homeland security,...
Ngày tải lên: 17/02/2014, 11:20
... the active site Ser of the protease to the carboxyl group of P 1 by an ester bond and insertion of the N-terminal part of the RCL as strand 4 in b-sheet A (s4A) of the serpin. Consequently, the ... as percentage of the theoretical maximum. The activity was monitored over time and the rate of latency transition expressed as the functional half-life, t ½ . The averag...
Ngày tải lên: 20/02/2014, 11:20
Đề tài " The strong Macdonald conjecture and Hodge theory on the loop Grassmannian " docx
... −z n .(6.3) The summands are the w-transforms of the quotient of the (T,z,t)-character of the fibre p (−t) p Gr Ω p at the base-point of X by the Kac denominator. The sum expands into a formal ... lim n H ∗ (X;Ω p /Z n Ω p ) and the proposition. Our main theorem describes the Dolbeault groups of X and the action thereon of de Rham’s operator ∂ :Ω p → Ω p+1 . Th...
Ngày tải lên: 06/03/2014, 08:21
Báo cáo khoa học: Identification, subcellular localization and functional interactions of PilMNOWQ and PilA4 involved in transformation competency and pilus biogenesis in the thermophilic bacterium Thermus thermophilus HB27 ppt
... in the assembly and stability of PilQ multimers at the inner membrane and transport of these subassemblies to the outer membrane. The presence of the pilin-like PilA4 protein in the inner and ... within the Bacteria deserving the taxonomic status of a phylum [1,2]. Thermus represent- atives, such as Thermus thermophilus strain HB27, Thermus thermophilus HB8, Thermus flavu...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Contributions to catalysis and potential interactions of the three catalytic domains in a contiguous trimeric creatine kinase doc
... 2). The V max and k cat values for the D1 S D2D3 mutant were significantly higher than the values for the D1D2 S D3 and D1D2D3 S mutants (values for the latter two were not different from each other). ... active, respectively, than the wild-type FlgCK (Table 2 and Fig. 2). The V max and k cat values for the D1 S D2D3 S mutant were significantly higher than the values f...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khóa học: The C-terminal t peptide of acetylcholinesterase forms an a helix that supports homomeric and heteromeric interactions potx
... at the end of the catalytic domain ()5to )1) and in the t peptide, at the beginning (1 to 6), in the middle (19 or 21), or near the end (34, 35 or 36), in the presence or in the absence of the ... we analyse the structural basis for the hydrophobic and quaternary interactions of the t pep- tide. In particular, we ask whether hydrophobic interactions result from...
Ngày tải lên: 30/03/2014, 13:20
Báo cáo khoa học: "Dependency trees and the strong generative capacity of CCG" pot
... (Vijay-Shanker and Weir, 1994), there are few results about the strong generative capacity of CCG. This makes it difficult to gauge the similarities and differences between CCG and other formalisms in how they ... forward and backward application; the cases for n > 0 where the slash before B n is the same as the slash be- fore B are called composition of degree n ;...
Ngày tải lên: 31/03/2014, 20:20
The mandibles of a mantis are strong and sharp enough to cut human flesh potx
... The mandibles of a mantis are strong and sharp enough to cut human flesh *The mandibles of a mantis are strong and sharp enough to cut human flesh. ... The mandibles of a mantis are strong and sharp enough to cut human flesh. 2. Các bạn hãy di chuột vào từng cụm từ một để biết chức năng của cụm trong câu: The mandibles of a mantis are strong ... tiền, tôi s...
Ngày tải lên: 02/04/2014, 21:21
bilenky, hosek. glashow-weinberg-salam theory of electroweak interactions and their neutral currents
Ngày tải lên: 24/04/2014, 17:16