... biological effect relies on two critical con-ditions, the presence of Ca2–CPP aggregates in the cor-rect conformation and concentration, and a suitableratio between Ca2+ and CPP, this latter conditionbeing ... undergo differentia-tion in culture, and demonstrates that this biological effect depends on a particular type of CPP aggrega-tion and the concentration of aggregates in solution.For the first time, ... calibration constant, dn ⁄ dc is the refractiveindex increment of the solution, c is the CPP concentra-tion (gÆmL)1), cnis the concentration of CPP formingparticles of molecular mass Mn, and...