... SCI-ENTIFIC AMERICAN, 415 Madison Ave-nue, New York, N.Y. 1001 7-1 111, or fax(212) 35 5-0 408.Photocopying rights are hereby grant-ed by Scientific American, Inc., to li-braries and others registered ... diversi-ty springs from the size of these mini-gene families: there are more than 100kinds of V (variable) genes, 12 D (diver-sity) genes and four J (joining) genes. The C, or constant, genes ... complete V-D-J-C gene. This genetic rearrange-ment allows for 4,800 diÝerent vari-eties (100 × 12 × 4 × 1) of heavy chains.The same process occurs in the assem-bly of the light-chain genes, ...