... 36–44% and 38% as active as AdoCbl indiol dehydratase [27,43,44] and glycerol dehydratase[44], respectively, but it serves as a strong competitiveinhibitor for ethanolamine ammonia-lyase [44] and ribonucleotide ... reductase [29] and a weak competitiveinhibitor for methylmalonyl-CoA mutase [44]. 2¢-De-oxyAdoCbl is 31%, 17%, and 5–13% as active as Ado-Cbl for diol dehydratase [38,45], glycerol dehydratase[41], ... homoadenosylcobalamins for diol dehydratase and ethanolamine ammonia-lyase.It was shown that these analogues would be useful for obtaining information about the distance between Co and C5¢, which is critical for...