... sequence analysis: probabilistic models ofproteins and nucleic acids. Cambridge University Press,Cambridge.26 Eddy SR (1998) Profile hidden Markov models. Bioinformatics 14, 755–763.SDR classification ... we apply hidden Markov models (HMMs) to obtain a sequence-basedsubdivision of the SDR superfamily that allows for automatic classification of novel sequence data andprovides the basis for a nomenclature ... short-chain dehydrogenase⁄reductasesuperfamily using hidden Markov models Yvonne Kallberg1,2, Udo Oppermann3and Bengt Persson1,2,41 IFM Bioinformatics, Linko¨ping University, Sweden2 Department...