signal transduction and human disease

... plaque for- Signal Transduction and Human Disease, Edited by Toren Finkel and J. Silvio Gutkind ISBN 0-471-02011-7 Copyright © 2003 John Wiley & Sons, Inc. 2 ATHEROSCLEROSIS: SIGNAL TRANSDUCTION ... mechanistically by their ability to induce a prooxidant state. SIGNAL TRANSDUCTION AND HUMAN DISEASE 6 ATHEROSCLEROSIS: SIGNAL TRANSDUCTION BY OXYGEN AND NITROG...

Ngày tải lên: 11/04/2014, 10:31

Ngày tải lên: 23/03/2014, 03:20

... models and human diseases Wiljan J. A. J. Hendriks 1 , Ari Elson 2 , Sheila Harroch 3 and Andrew W. Stoker 4 1 Department of Cell Biology, Radboud University Nijmegen Medical Centre, The Netherlands 2 ... systems and the study of various human disease states have begun to elucidate the important and diverse roles of protein tyrosine phosphatases in cellular sig- nalling pathways...

Ngày tải lên: 30/03/2014, 04:20

... (GAP) in Ras Signal Transduction 368 9.6 Guanine Nucleotide Exchange Factors (GEFs) in Signal Transduction via Ras Proteins 369 9.6.1 General Function of GEFs 369 9.6.2 Structure and Activation ... Proteins 406 11.3 T and B Cell Antigen Receptors 409 11.3.1 Receptor Structure 410 11.3.2 Intracellular Signal Molecules of the T and B Cell Antigen Receptors 411 11.4 Signal Tra...

Ngày tải lên: 08/04/2014, 12:41

... 1. Signal Transduction 1.1 Integration of Metabolism and Survival S1.1-1 Regulation of metabolism by estrogen signaling J. Gustafsson, R. Rodrigo and W. Warner Department of BioSciences and ... ERa and ERb and their influence on regulation of GLUT4, and its associated structural protein, caveolin-1, in mouse muscle. ERa and ERb are co-expressed in the nuclei of most muscle ce...

Ngày tải lên: 19/02/2014, 07:20

... and T. H. MacRae Small heat shock proteins and disease FEBS Journal 272 (2005) 2613–2627 ª 2005 FEBS 2627 REVIEW ARTICLE The small heat shock proteins and their role in human disease Yu Sun and ... mammalian lens and guard against ischemic and reper- fusion injury due to heart attack and stroke. On the other hand, mutated sHSPs are implicated in diseases such as desmin-rel...

Ngày tải lên: 19/02/2014, 18:20

... Lactobacillus and Bifidobacterium and by binding microbial antigens. The glycoconjugates bind specific bacterial (V. chol- erae) and viral ligands (rotavirus). Lipid, the third major nutrient and energy ... rhinitis or anaphylaxis; autoimmune disease systemic lupus erythematosus or inflammatory bowel disease; and chronic diseases—diabetes mellitus or coronary artery disease. In eac...

Ngày tải lên: 22/02/2014, 05:20

... splicing: role of pseudoexons in human disease and potential therapeutic strategies Ashish Dhir and Emanuele Buratti International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, ... cause of human disease is more frequent than previously thought. Here we aim to provide a review of the mechanisms that lead to pseudoexon activation in human genes and how th...

Ngày tải lên: 06/03/2014, 09:22

... protein and cytochrome b in the yeast bc 1 complex owing to a human disease- associated mutation within cytochrome b Nicholas Fisher 1 , Ingrid Bourges 1 , Philip Hill 1 , Gael Brasseur 2 and Brigitte ... interaction between the iron– sulfur protein headgroup and the quinol oxidation site, as judged by the electron paramagnetic resonance signal, and only a minor effect on the rate...

Ngày tải lên: 07/03/2014, 15:20

... FEBS The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B 1 and B 2 bradykinin receptors Alexander Faussner 1 , Alexandra Bauer 1 , Irina Kalatskaya 1 , ... (1998) Influence of the cytosolic carboxyl termini of human B 1 and B 2 kinin receptors on receptor sequestration, ligand internalization, and signal transduction. J Biol...

Ngày tải lên: 07/03/2014, 16:20