protein misfolding and disease
protein misfolding and disease
... Gregersen Protein Misfolding and Disease Principles and Protocols Protein Misfolding and Disease Principles and Protocols Edited by Peter Bross Niels Gregersen In Vivo Protein Folding and Defects ... G., and Dob- son, C. M. (2002) Kinetic partitioning of protein folding and aggregation. Nat. Struct. Biol. 9, 137–143. 30. Soto, C. (2001) Protein misfolding an...
Ngày tải lên: 11/04/2014, 10:12
Báo cáo khoa học: Protein-misfolding diseases and chaperone-based therapeutic approaches pdf
... Chaudhuri and S. Paul Protein- misfolding diseases FEBS Journal 273 (2006) 1331–1349 ª 2006 The Authors Journal compilation ª 2006 FEBS 1349 REVIEW ARTICLE Protein- misfolding diseases and chaperone-based therapeutic ... neurodegenerative diseases in humans result from pro- tein misfolding and aggregation. Protein misfolding is believed to be the primary cause of Alzheimer’s...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Hyperefficient PrPSc amplification of mouse-adapted BSE and scrapie strain by protein misfolding cyclic amplification technique pptx
... encephalopathies (TSEs), or prion diseases, are a series of fatal neurodegenerative diseases that include Creutzfeldt–Jakob disease (CJD) in humans, scrapie in sheep and bovine spongiform encephalopathy ... spongiform encephalopathy; CJD, Creutzfeldt–Jakob disease; mBSE, mouse-adapted BSE; NBH, normal brain homogenate; PK, proteinase K; PMCA, protein misfolding cyclic amplification; P...
Ngày tải lên: 23/03/2014, 04:21
Báo cáo Y học: Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations pdf
... sheet structure and increased protease resistance, suggesting that the protein can no longer be cleaved at this point. Prion diseases are fatal neurodegenerative diseases. In these diseases, PrP c is ... avoid major degradation of the protein and no gradient was applied to the DE52/CM52 column during purification. Full length protein (PrP23–231) and other recombinant proteins equiv...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... 2870.7Da, 3084Da, 9180.5Da, and 13748.8Da, respectively. Among the four proteins, two proteins with m/z 2870.7 and 3084 were down-regulated, and the other two with m/z 9180.5 and 13748.8 were up-regulated ... serum protein fingerprint of patients with colorectal cancer (CRC) and to screen protein molecules that are closely related to colorectal cancer during the onset and...
Ngày tải lên: 25/10/2012, 11:18
Tài liệu OXIDATIVE STRESS AND DISEASES pptx
... resistin and visfatin, as well as cytokines and chemokines such as TNF-, IL-6 and monocyte chemoattractant protein (Antuna-Puente et al., 2008) and due to the dramatic rise in obesity and its ... Stress and Impaired Cardiovascular Functions 101 formation and angiogenesis, insulin resistance, adipogenesis and T-lymphocyte activation) and is deregulated in human disea...
Ngày tải lên: 12/02/2014, 16:20
Tài liệu NIEHS/EPA Children’s Environmental Health and Disease Prevention Research Centers: Protecting Children’s Health for a Lifetime pptx
... range of pollutants and compounds and their potential effects on development and learning. Environmental factors in diseases such as asthma, immune disorders, autism, and obesity are also ... intervention and prevention methods and strategies. n Enhance communication, innovation and research. n Promote multidisciplinary interactions among basic scientists, clinicians and b...
Ngày tải lên: 12/02/2014, 19:20
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... BTK–SYK and ITK– SYK fusion proteins lead to differential phosphorylation levels of the fusion proteins themselves, as well as the downstream adapter proteins SLP76 and BLNK, in 293T and COS7 ... ª 2011 FEBS MINIREVIEW TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK Alamdar Hussain 1,2, *, Liang Yu...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... is a putative protein protein interaction module. Four KIND-containing proteins, Spir-2 (actin-nuclear factor), PTPN13 (protein tyrosine phosphatase), FRMPD2 (scaffold protein) and very-KIND ... Sports, Science and Technology; the Japan Society for the Promotion of Science; and the Japan Science and Technology Agency. References 1 Pawson T & Nash P (2000) Protein protein int...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Insects and Diseases pptx
... with malaria and other diseases caused by mosquitoes. WILSON, J.C. Modern Clinical Medicine; Infectious Diseases. New York and London, 1905. Chapters on yellow fever, malarial diseases and plague; ... Bacteria, 177; Insects and disease, 178; Mosquitoes systematic and general, 179; Mosquito anatomy, 182; Mosquitoes life-history and habits, 183; Mosquito fighting, 183; Mosquitoes...
Ngày tải lên: 17/02/2014, 22:20