pharmacokinetics and metabolism in drug design
pharmacokinetics and metabolism in drug design
... 3-527-60021-3 (Electronic) Pharmacokinetics and Metabolism in Drug Design by Dennis A. Smith, Han van de Waterbeemd and Don K. Walker Pharmacokinetics and Metabolism in Drug Design Edited by D. ... Oxidative Metabolism and Drug Design 85 7.3 Oxidative Metabolism and Drug Design In addition to the examples indicated above the design of orally-a...
Ngày tải lên: 11/04/2014, 10:03
Báo cáo khoa học: Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism docx
... poly- morphisms in CYP2D6 can significantly affect the activity of the enzyme, and therefore serve as an important guideline for determining the dose of anti- depressant drugs and preventing drug- induced ... in which total protein bound and imported into mitochondria is present; T, trypsin-treated mitochondria in which only the protein imported into mitochondria is present. In...
Ngày tải lên: 29/03/2014, 23:20
Tài liệu Friction and Lubrication in Mechanical Design P2 doc
Ngày tải lên: 13/12/2013, 03:15
Tài liệu Friction and Lubrication in Mechanical Design P1 pdf
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Ngày tải lên: 13/12/2013, 03:15
Tài liệu Lipases and Phospholipases in Drug Development pptx
... Alkaline Sphingomyelinase from the Intestinal Tract 85 5.2.1.6 Bacterial Sphingomyelinase-phospholipase C 85 5.2.2 Sphingomyelinase Mechanism 85 5.2.2.1 Binding of Magnesium Ions 85 5.2.2.2 Binding ... Sphingomyelinase Assay 88 5.2.4 Sphingomyelinase Inhibitors 89 5.3 Sphingomyelinase–Membrane Interactions 89 5.3.1 Lipid Effects on Sphingomyelinase Activity 90 5.3.2 Effects of Sphingomyelinas...
Ngày tải lên: 17/02/2014, 05:20
MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION docx
... 4 Drug- Metabolizing Enzymes, Transporters, and Drug Drug Interactions STEVEN W. LOUIE, and MAGANG SHOU Department of Pharmacokinetics and Drug Metabolism, Amgen, Inc., Thousand Oaks, ... described in Chapter 7. In this chapter, the reader will obtain insight into the strategies used to design experiments for characterizing drug metabolism properties and addressing...
Ngày tải lên: 28/03/2014, 10:20
Working with the Fogbow Design and reconfiguration of services and participation in e-Government
... accountability 67 issues and influence, the authorities had visions of establishing a chain of interlinking anchoring-processes in order to sustain responsibility of interaction and management. Things did ... the interaction as a constant activity of consultation and listening, deliberation and “thinking upon” the citizens. In local practice the linking of citizen’s services...
Ngày tải lên: 04/11/2013, 20:15
A STUDY ON ENGLISH EXPRESSIONS USED IN WEBSITE DESIGN AND VIETNAMESE EQUIVALENCE
... paper mainly focuses on: Pointing out the definition of web language, the process of designing web pages, classifying of static and dynamic website languages Collecting and presenting some ... Translation by paraphrasing using unrelated word 50 4.5 Addition and omission 51 CHAPTER III: MAIN FINDINGS 51 I. Common Mistakes in understanding...
Ngày tải lên: 11/12/2013, 23:48
The Anatomy of Design: Uncovering the influences and inspiration in modern graphic design
... print. “Shipping it actually cost more than the printing, if you can believe it.” The campaign worked so effectively in stamping the brand in the consumer’s mind that Urban Outfitters retained ... Architecture and Building Engineering, Tokai University, designed by Masayoshi Kodaira, use distinct yet interconnecting images (in this case, letterforms) to spell out a larger message. Di...
Ngày tải lên: 13/02/2014, 17:41