gene therapy protocols, 2nd
... Press M E T H O D S I N M O L E C U L A R M E D I C I N E TM Gene Therapy Protocols Edited by Jeffrey R. Morgan Second Edition Gene Therapy Protocols Second Edition Edited by Jeffrey R. Morgan 20 ... useful target cells for gene deliv- ery, as they are highly active metabolically, have a substantial blood supply 15 From: Methods in Molecular Medicine, Vol. 69, Gene Therapy...
Ngày tải lên: 10/04/2014, 22:53
gene therapy protocols
... D. T. (1994) Receptor-mediated gene delivery employing lectm-bmdmg specificity. Gene Ther 1,255-260. 40. Morgan, R. A. and Anderson, W. F. (1993) Human gene therapy. Ann Rev. Biochem 62, 191-217. ... employment for those gene therapy applications requiring cell-specific delivery of therapeutic genes. Finally, the molecular conjugate vector system is devoid of viral gene elem...
Ngày tải lên: 11/04/2014, 09:42
... HSV-tK Effector Gene David Bermudes, Brooks Low, and John M. Pawelek 419 Part II. Clinical Protocols for Cancer Gene Therapy A: Immunotherapy/Tumor Vaccination 27 Ex Vivo Cytokine Gene Transfer ... APPROACHES IN CANCER GENE THERAPY A: Immunotherapy/Tumor Vaccination Cytokine-Transduced Tumor Cells 3 3 From: Methods in Molecular Medicine, Vol. 35: Gene Therapy: Methods and...
Ngày tải lên: 11/04/2014, 09:42
... Findeis Nonviral Vectors for Gene Therapy Methods and Protocols Humana Press Humana Press Edited by Mark A. Findeis Nonviral Vectors for Gene Therapy Methods and Protocols 20 Niidome and Aoyagi internalization ... targeted gene transfer has also been realized by modification of the gene carriers using cell-targeting ligands such as asialoorosomucoid, transferrin, insulin, or g...
Ngày tải lên: 11/04/2014, 09:59
Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"
... E2b genes and the use of homologous (rat) BMP genes do not improve the osteogenic potential of direct BMP adenovirus vector gene therapy, the results of this study indicate that BMP gene therapy ... immunocompetent animals. 1. INTRODUCTION Gene therapy provides a novel method to repair damaged bone by using bone morphogenetic protein (BMP). BMP gene vectors can be divided i...
Ngày tải lên: 31/10/2012, 17:08
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... to human germline gene therapy. 2. Criteria for Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have ... for human germline gene therapy. The lack of human ESCs leaves NT-based gene transfer as the only method that might be able to permit gene targeting in human germline gene the...
Ngày tải lên: 03/11/2012, 10:01
sermina lieu phap gen human gene therapy
... dục. nguyenthanhloi_2@yahoo.com 54 TRƯỜNG ĐH TÂY NGUYÊN KHOA KHTN & CN LIỆU PHÁP GEN (Human Gene Therapy) GVHD: Võ Thị Phương Khanh SVTH: Nguyễn Thành Lợi Hồ Thị Lan Anh Nguyễn Thị Trang nguyenthanhloi_2@yahoo.com ... bắn gen, các vi đạn có bọc gen liệu pháp để đưa vào tế bào đích Kỹ thuật dùng súng bắn gen (gene gun): nguyenthanhloi_2@yahoo.com 14 Kỹ thuật liposom (liposom te...
Ngày tải lên: 06/09/2013, 22:49
Gene Therapy - Tools and Potential Applications by Francisco Martin Molina Contributors ppt
... addressed and the gene types transferred in gene therapy clinical trials, re‐ spectively [6]. Indications addressed by gene therapy clinical trials Cancer diseases Cardiovascular diseases Gene marking Healthy ... most important, and most difficult, challenge in gene therapy is the issue of delivery. The tools used to achieve gene modification are called gene therapy vect...
Ngày tải lên: 17/03/2014, 21:20
Novel Gene Therapy Approaches Edited by Ming Wei and David Good pdf
... Introduction Gene therapy is a promising approach to treat intractable and refractory diseases at the genetic level. Basically, in gene therapy, target gene expression is induced by delivering foreign genes. Downregulation ... of target gene expression or gene silencing can also be performed using miRNA, siRNA or shRNA expression vectors [1]. Gene therapy is useful for both g...
Ngày tải lên: 23/03/2014, 14:20
Báo cáo Y học: In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors pdf
... used for the delivery and expression of the IDUA gene to cells in vivo for treatment of MPS I. Keywords: MPS I; Hurler syndrome; a- L -iduronidase; gene therapy. Mucopolysaccharidosis type I (MPS I) ... vector to mediate gene transfer and expression in appropriate targets in vivo (muscle, brain, hematopoietic cells) and correct GAG storage in murine MPS I cells as a model for gene...
Ngày tải lên: 24/03/2014, 04:21