... Epidemiology at Harvard; and David L. Katz, M.D., M.P.H., Asso-ciate Professor of Public Health at Yale and Director of the Prevention Research Center, all of whom not only kindly and charitably read ... maintenance gone awry, has been called a brain disease, a metabolic disease, a genetic disease, and even a disease of inflammation. Bray (2004) considers obesity a “neurochemical” disease. ere ... the idea that obesity “meets all the criteria of a medical disease, including a known etiology, recognized signs and symptoms, and a range of structural and functional changes that culminate...