Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot

Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt

Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt

... and ultimately abolished, the increase in c-myc gene expression elicited by PMA in serum-free cells. These results suggest that inhibition of MEK/ERK signaling by NAMI-A may have an important role in modulating ... be lying upstream of ERK1/2. Recent observations indicate that activation of Raf by PMA may trigger the same signaling pathway as oncogenic Raf, or Raf activati...
Ngày tải lên : 21/02/2014, 01:21
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Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc

Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc

... hardly inhibited by MU up to 1.0 m M (data not shown). This result suggest that the inhibition of HA production was not caused by direct inhibition of HAS activity. Effect of MU on HAS activity in ... HA released into the culture medium was measured by the sandwich binding protein assay using hyaluronan binding protein (HABP) according to the manufacture’s instructions for t...
Ngày tải lên : 08/03/2014, 09:20
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Báo cáo Y học: Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin potx

Báo cáo Y học: Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin potx

... mgÆmL )1 providing complete inhibition of apoC-II amyloid formation, equivalent to a 30 : 1 molar excess of apoC-II to clusterin (Fig. 1B). The specificity of the inhibition of amyloid formation by clusterin ... levels of clusterin, derived from either plasma or semen, potently inhibit amyloid formation by apoC-II. Inhibition is dependent on apoC-II concentration, with more...
Ngày tải lên : 24/03/2014, 04:21
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Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot

Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot

... Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues Cristiana Santos de Macedo, Peter ... study glycosylphosphatidylinositol (GPtdIns) biosynthesis and GPtdIns protein anchoring in protozoal and mammalian systems. The effects of these analogues on GPtdIns biosynthesis and GPtdIns-protein ... t...
Ngày tải lên : 31/03/2014, 23:20
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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

... was reduced by 60% in the presence of 500 l M Cl-tetracycline and by 95% in t he presence of 500 l M erythromycin and streptomycin (Fig. 2B,C). Tetracycline at 500 l M inhibited splicing by only 1 0% ... splicing inhibition by tetracycline is n egligible (Fig. 2). The sixfold stron ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and...
Ngày tải lên : 21/02/2014, 15:20
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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

... processes including: activation of apoptosis in Jurkat T-cells [5], inhibition of platelet aggregation [6,7] and inhibition of in ammatory cytokine production in macrophages [8]. Curcumin has also ... activity of a number of key enzymes such as cyclooxygenase [9], protein kinase C [10], protein tyrosine kinases [11] and a Ca 2þ -dependent endonuclease [12]. Many of these...
Ngày tải lên : 08/03/2014, 23:20
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Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt

Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt

... permeability studies The effect of 2-APB on membrane permeability was monitored by assessing the quenching of calcein dye trapped in egg phosphatidylcholine liposomes by Co 2+ , as described by Longland ... inhibition of SERCA (Eur. J. Biochem. 269) 3687 Inhibition of SERCA Ca 2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca 2+ binding and phosphory...
Ngày tải lên : 31/03/2014, 23:20
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Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"

Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"

... with clinically and pathologically proven steatosis and 98 patients without steatosis were recruited into this study. The levels of fasting blood glucose (FBG), fasting insulin (FINS), triglyceride ... levels of serum alanine aminotransferase (ALT). The higher prevalence of hepatic steatosis in Hispanics was mainly due to the higher prevalence of obesity and insulin resistance...
Ngày tải lên : 25/10/2012, 11:48
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Báo cáo y học: "Management of HBV Infection in Liver Transplantation Patients"

Báo cáo y học: "Management of HBV Infection in Liver Transplantation Patients"

... contributing to the efficacy of combination LAM and HBIG remain poorly defined. Postulated mechanisms include the synergy of: 1) LAM reducing HBV replication and altering synthesis of HBsAg necessary ... finding of circulating HBV DNA by PCR in 2 of 11 receiving HBIG and 5 of 10 receiving LAM suggests that reinfection would be likely in additional patients with longer obse...
Ngày tải lên : 02/11/2012, 11:17
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Tài liệu Báo cáo khoa học: Inhibition of pea ferredoxin–NADP(H) reductase by Zn-ferrocyanide docx

Tài liệu Báo cáo khoa học: Inhibition of pea ferredoxin–NADP(H) reductase by Zn-ferrocyanide docx

... Similarly, replacing Tyr308 with other aromatic amino acids only slightly affects the inhibition by Zn-ferrocyanide on the enzyme. In contrast, replacing Tyr308 with glycine or serine consider- ably ... Zn-ferrocyanide. Effect of Fld on the inhibition of FNR activities by Zn-ferrocyanide In some photosynthetic systems, such as that of certain algae and cyanobacteria, the FMN...
Ngày tải lên : 19/02/2014, 16:20
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