Báo cáo Y học: Nuclear receptor-dependent transcription with chromatin Is it all about enzymes? pot
Báo cáo Y học: Nuclear receptor-dependent transcription with chromatin Is it all about enzymes? pot
... MINIREVIEW Nuclear receptor-dependent transcription with chromatin Is it all about enzymes? W Lee Kraus 1,2 and Jiemin Wong 3 1 Department of Molecular Biology and Genetics, Cornell University, Ithaca, ... are functionally linked. Although H3 phosphorylation has not yet been demonstrated to play a role in NR-dependent transcription with chromatin, it seems likely to...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... in the promoter of the MT gene possesses transcriptional regulatory activity and that a variety of nuclear transcription factors interact specifically with MREa [11,33,38,39]. These findings suggest ... consistency with the immunoblot analysis result, the mRNA level of WD gene was signifi- cantly diminished from 0.5 to 12 h after transfection and then completely restored to wild-type lev...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle docx
... carboxylate oxygens) lain manually in the dUSP ligand-binding pocket with the carboxy and distal (epoxy) ends, respectively, situated in similar regions of the pocket as the carboxyl end and distal ... does 9-cis RA interact with Cys432 and His435 in hRXRa (Fig. 3B–D). We tested this model by overexpressing the His-tagged dUSP double mutant Cys472Ala/His475Leu (C472A/ H475L) in methyl epo...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo y học: "Treat Ankylosing Spondylitis with Methazolamide"
... carbonic anhydrase I; BASDAI: Bath AS disease activity index; BASFI: Bath ankylosing spondylitis functional index; RA: rheumatoid arthritis; OA: osteoarthritis; ESR: erythrocyte sedimentation ... spinal deformity and fusion (1). The disease usually takes a chronic course that is characterized by bone resorption and new bone formation with syndesmo- phytes and ankylosis (1). The co...
Ngày tải lên: 25/10/2012, 10:56
Báo cáo y học: " Bronchial Anthracofibrosis Case with Endobronchial Tuberculosis"
... The typical characteristics of patients with bronchial stenosis due to anthracofibrosis are elderly women, without a prior history of pneumoconiosis or smoking, a chief complaint of cough without ... was positive re- vealing mycobacterium tuberculosis and sensitive to all major tuberculosis agents. Treatment and clinical course Tuberculosis treatment was initiated with iso- niazid...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"
... Acute Toxicities A definitive 5-FU/CDDP-based CRT is associ- ated with acute toxicities, predominantly leucopenia, stomatitis, and cheilitis [5-9,18]. Toxicity was evalu- ated using criteria defined ... toxicities may be predicted on the basis of genetic polymorphisms. CDDP is one of the antitumor agents most widely used against several types of solid tumors. However, its clinical...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo y học: "Malignant phyllodes tumor with heterologous liposarcomatous differentiation and tubular adenoma-like epithelial component"
... partially with eosinophilic proteinaceous material, without atypia or mitotic activity, typically seen in a tubular adenoma of the breast (Fig.4,5). These glands contained a prominent myoepithelial ... case A 30-year-old woman presented with a 1-year history of a palpable, asymptomatic right breast mass. There was no family history of breast carcinoma. No axillary lymphadenopathy...
Ngày tải lên: 31/10/2012, 16:57
Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"
... Japanese en- cephalitis serogroup. WNV infection is a zoonotic disease transmitted by a mosquito vector (type Culex), with wild birds serving as its reservoir. The disease is endemic in Europe, ... creamy lesions on ophthalmoscopy, with early hyopofluorescence and late staining on fluorescein angiography (FA). Inac- tive chorioretinal lesions typically are partially atro- phic an...
Ngày tải lên: 03/11/2012, 11:17
Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"
... initially diagnosed with epilepsy had syncope with convulsive activity due cardiovascular etiology [20, 21, 22]. The pathophysiology of syncope provoked convulsive activity is complex. Asystole ... atrio- ventricular re-entrant tachycardia with HR (200). These episodes of arrhythmias either tachycardia or bradycardia were associated either with syncope during ILR monitoring....
Ngày tải lên: 03/11/2012, 11:17
Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot
... interact with decorin. One possible explanation o f this d iscrepancy could lie in the fact that type II collagen is more glycosylated than type I collagen. It seems to us probable that glycosylation ... chromatography for the two smallerpeptides[27,30]. All collagens and peptides were analyzed for purity by means of a quantitative Hyp assay [38], electrophoresis in denaturing conditi...
Ngày tải lên: 21/02/2014, 15:20