Báo cáo Y học: Beyond the ABCs of CKC and SCC Do centromeres orchestrate sister chromatid cohesion or vice versa? potx

... SCC Do centromeres orchestrate sister chromatid cohesion or vice versa? Pamela B. Meluh 1 and Alexander V. Strunnikov 2 1 Memorial Sloan-Kettering Cancer Center, Laboratory of Mechanism and Regulation ... nature of centromeric chromatin, the dynamics and regulation of sister chromatid cohesion, and the relationship between the two. Keywords: centro...

Ngày tải lên: 31/03/2014, 21:21

... that the MET to be at least the equivalent of the pre-existing cardiac arrest team and consist of at least one doctor and a nurse from the emergency department or ICU. A 6-month study period ... by use of regular reminders until the first day of the study period. The staff designated to form the MET varied between participating centers because of local cir...

Ngày tải lên: 25/10/2012, 10:39

... adminis- tered orally [27]. Therefore, the aim of the present study was to evaluate the inhibitory effect of some thioglycosides synthesized in our laboratory on human hSGLT1 and hSGLT2 –as ... seg- ment of the tubule. Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the cont...

Ngày tải lên: 26/10/2012, 10:04

... an enzyme with slightly lower stability. On the other hand, in the double mutant G261A /Y2 69A the additional replacement of Tyr269 by Ala restores the stability of the protein producing a more stable ... phosphatase was built [21] on the basis of the homology to the E.colienzyme the structure of which is known [24]. For display of the model and for design and...

Ngày tải lên: 22/02/2014, 04:20

... backbone by trifluoroethanol molecules, the proton donator/acceptor properties of the trifluoroethanol molecule for hydrogen bonds and the influence of trifluoroethanol on the dielectric constant of the ... hydro- chloride (GdnHCl), urea or elevated temperatures, they destroy the tertiary structure of proteins which results in the loss of enzymatic activity. Regarding...

Ngày tải lên: 22/02/2014, 07:20

... when studying the catalytic efficiency for these mutants in the diaphorase reaction, all of them yield values very close to those of the wild-type enzyme at the different ionic strengths assayed (within ... (for E139D and E139K) and 64% (for E139Q) of that found for the wild-type enzyme (Table 4). Therefore, although it is not possible to quantify exactly the magnitude o...

Ngày tải lên: 31/03/2014, 08:20

... closed. Severity of ab- normalities in each category are rated by the subject and technician, with a range of scores for nausea of 0 to 16, for skin color of 0 to 8, for cold sweating of 0 to 8, ... received R on one testing day and P on the other. The order of treatment was determined randomly by the inde- pendent pharmacists, who created the randomization sche...

Ngày tải lên: 26/10/2012, 09:57

... away from the issue of seman- tic feedback to syntactic processing primarily due to the difficulty of getting the communication be- tween syntax and semantics to work in a clean and systematic ... trees, For each word, Add a new node T~ to the current forest of trees {Ti} for each category for the word in the lexicon mark T~ as a complete subtree Repeat until t...

Ngày tải lên: 20/02/2014, 21:20

... gives the upper bound on the accuracy of the CCG parser. Results are calcu- lated using both gold standard and automatically assigned POS tags; # is the number of sentences in the sample, and the ... details of the two parsers. 53 shows that converting gold-standard CCG deriva- tions into the GRs in DepBank resulted in an F- score of only 85%; hence the upper bou...

Ngày tải lên: 17/03/2014, 02:20

... phrase subordination in another, and intersentential co- hesion in yet another context. Likewise, the other tunes perform slight variations on the function of continue and segment according ... lying non-linguistic goals. It is through the frame- work of games and their components, conversa- tional moves, that the intonation of mono- and di-syllabic words can...

Ngày tải lên: 17/03/2014, 08:20