Báo cáo Y học: When the embryonic genome flexes its muscles Chromatin and myogenic transcription regulation ppt

... MINIREVIEW When the embryonic genome flexes its muscles Chromatin and myogenic transcription regulation Ralph A. W. Rupp 1 , Nishant Singhal 1 and Gert Jan C. Veenstra 2 1 Adolf-Butenandt-Institut, ... for example for the lysozyme gene in myeloid cells [67], and for the b-globin gene in erythrocytes [68]. Priming by SWI/SNF complexes may even apply to the m...

Ngày tải lên: 31/03/2014, 21:21

... b-endorphin and other proopiomelanocortin products of the anterior pituitary gland. CRH is considered to be the key hormone in the control of the hypothalamic–pituitary–adrenal axis func- tion and is ... 3A shows the family of 40 structures and Table 1 contains a summary of statistical data indica- ting the quality of the 40 models and the average energy- minimized str...

Ngày tải lên: 17/03/2014, 10:20

... Exon2-mut-luc), and compared its activity to the activity of Exon2-luc in transient transfection assays. The mutation led to complete loss of activity in these assays, indicating that the integrity of the ... asynchronously growing cells (asynchr.) was also analyzed. The percentage of cells in the G0/G1, S, and G2/M phases of the cell cycle at each time point was determine...

Ngày tải lên: 08/03/2014, 09:20

... maintained by use of regular reminders until the first day of the study period. The staff designated to form the MET varied between participating centers because of local circumstances. The study protocol ... that the MET to be at least the equivalent of the pre-existing cardiac arrest team and consist of at least one doctor and a nurse from the emergency department...

Ngày tải lên: 25/10/2012, 10:39

... but rather a starting point to inform readers and stimulate more thought and investigation as to the most appropriate statistical methods to use and the theory and assumptions behind them. Keywords ... the series include: standard errors and confidence intervals; hypothesis testing and errors; power calculations; measures of disease; parametric and non-parametric tests; si...

Ngày tải lên: 25/10/2012, 10:45

... b(H n L), j and n ¼ 2, except for DAHKam, where j ¼ 1 and n ¼ 3. b Ni(II) data from ref [11]. c [31]. d [36]. e glycylglycylhistamine, [9]. f a-hydroxymetylseryl-a-hydroxymetylserylhistidinamide; ... Bal 1,2 1 Faculty of Chemistry, University of Wroclaw, Poland; 2 Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland A comparative study of thermodynamic a...

Ngày tải lên: 22/02/2014, 04:20

... resulted in an enzyme with slightly lower stability. On the other hand, in the double mutant G261A /Y2 69A the additional replacement of Tyr269 by Ala restores the stability of the protein producing ... of the psychrophilic alkaline phosphatase was built [21] on the basis of the homology to the E.colienzyme the structure of which is known [24]. For display of the model...

Ngày tải lên: 22/02/2014, 04:20

... detected by proteolysis (see below), we investigated RNase A in the absence and presence of 20% trifluoroethanol by NOESY and TOCSY NMR spectroscopy. However, due to the high pH value (8.0) and the ... P. Bayer, Max-Planck Institute of Molecular Physiology, Dortmund, Germany, for performing NMR spectroscopy experiments. The support for Jens Ko ¨ ditz by the Land Sachsen-Anhalt...

Ngày tải lên: 22/02/2014, 07:20

... prosequences from the recombinant allergen is facilitated by its N-glycosylation and that the truncated, activated allergen shows proteolytic activity, resulting in very low stability of the protein. ... conserved cysteine residues and other essential amino acids are numbered. Areas of high similarity exist around Cys69 and Cys72 and around Trp186, Trp193 and Trp197. The p...

Ngày tải lên: 08/03/2014, 22:20

... Sasaki, N., Okazaki, Y. , Muramatsu, M. & Hayashizaki, Y. (1988) Thermostabilization and thermoactiva- tion of thermolabile enzymes by trehalose and its application for the synthesis of full-length ... in the synthesis of trehalose-P and/ or free trehalose appear to have an important and probably essential function in the physiology of many organisms. The most widely de...

Ngày tải lên: 17/03/2014, 10:20