Báo cáo Y học: Inactivation of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio alginolyticus by reactive oxygen species pot
... uncoupling of the Na + -NQR activity by dioxygen In the presence of NADH and dioxygen, the purified Na + - NQR from V. alginolyticus was inactivated with a half time of approximately 3 min. This ... Sequence analysis of the six subunits of the Na + -NQR from V. alginolyticus (NqrA– NqrF) showed that only the NqrF (or b-) subunit comprises a cysteine motif (Cys69...
Ngày tải lên: 31/03/2014, 21:21
... efficiently oxidized by the enzymes of the respiratory chain, specifically designed for the NADH oxidation. However, the current study shows that superoxide is cata- lytically produced by the complex-bound ... 1e – oxidation of the carbanion in the E1 active site (a product of reaction 1) by highly electrophilic thiyl radical of the dihydrolipoyl residue of E2 ha...
Ngày tải lên: 21/02/2014, 01:21
... extracellular Na + , thereby protecting cells from intracellular acidification. The first known isoform of the protein was cloned in 1989 [1] followed by identification of six other isoforms to date, NHE2–NHE7 ... dimer and the NHE1 isoform specifically dimerizes to itself and not to other isoforms of the Na + /H + exchanger [5]. Although the NHE1 isoform of the Na + /H +...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo y học: "Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study"
... step forwards to assess the utility of these questionnaires in another practice setting. Therefore the aim of this observational study was to assess the utility of the MYMOP2 and W-BQ12 health outcomes ... utilised for the study. Patients were invited to participate in the study if they were: over the age of 18 years; had no treatment from any health professional for t...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... There was one boy who was being taken care of by the uncle. They stay in Langas. Langas was, let me say, it was the heat of the violence there. This boy is on second line medication, and at the ... and others were scarcely affected. They further noted that the quantitative data did not adequately capture the bravery of the AMPATH patients or the AMPATH staff. The int...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... im- proves later in the day. Some patients reported facial edema early in the morning and swelling of the legs at the end of the day. Participants were asked to weigh themselves using the same weighing ... re- duced to less than 300 grams. The frequency of edema was considered in the statistical analysis. The study was approved by the Research Ethics Committee...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... components by use of the inverse Diels Alder technology. The high chemical stability and the ease of synthesis qualify these polyamide building blocks as favourites for intracellular delivery and ... cyclopentene carboxylic acid chloride were purchased from Sigma Aldrich, Germany. The synthesis of the Reppe Anhy- dride was carried out as documented by Reppe [16]. T...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"
... balloon group compared with the other 2 groups (p<0.05).These findings were correlated with our study. In another study by Agrawal et al, the efficacy of the Valsalva maneuver on pain ... venous canulation could decrease the incidence and severity of pain associated with venipuncture in adult patients. 7 In another study by Gupta et al the efficacy of Int. J. Med...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"
... Synthesis of the PNA building block backbone In the next step, the synthesis of the PNA back- bone monomer using the fluorenylmethoxycarbonyl (Fmoc) protection occurred as described by Atherton ... Sheppard.[40] Synthesis of the Fmoc-C2-glycine-tert-butyl ester The synthesis of the peptide nucleic acid back- bone requires the introduction of protecting groups...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... group was similar as the frequency of 0.21 reported by Chen et al. in their study for chd patients derived from the lipoprotein coronary atherosclerosis study. Conversely, Skogsberg et al. ... 2004 from patients who attended the obesity and cardiology outpatient clinics of the University of Hamburg Hospital. Table 1 summarizes the patient characteristics. The vast...
Ngày tải lên: 31/10/2012, 17:03