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Báo cáo Y học: Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides Binding mode of vitamin K derivatives pptx

Báo cáo Y học: Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides Binding mode of vitamin K derivatives pptx

Báo cáo Y học: Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides Binding mode of vitamin K derivatives pptx

... Hucke et al.(Eur. J. Biochem. 269) Ó FEBS 2002 Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides Binding mode of vitamin K derivatives Oliver ... 1Õ), displaying the smallest value of the binding free energy, was considered for furtheranalysis. The binding site of the primary quinone in the reaction center protein from R. sphaeroides ... interactions may be important for t he binding of the physiological primary electron acceptor of the reaction center from B. viridis, vitamin K 1, which is a naphthoqui-none derivative. The aromatic...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

... G261A/ Y2 69A designed on the basis of side-chain packing criteria from a modelled structure of the enzyme resulted in restor-ation of the energy of activation to the levels of the nativeenzyme ... and the mutant can proceed with the catalysis as efficiently as the wild type (Fig. 3A). Investigation of the three-dimensionalhomology-based model of the enzyme revealed that the methyl group of ... XL1-MRF.Molecular modellingA three-dimensional molecular model of the psychrophilicalkaline phosphatase was built [21] on the basis of the homology to the E.colienzyme the structure of which isknown [24]....
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Báo cáo y học:

Báo cáo y học: "An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic"

... necessary to prevent the reappearance of this influenza. Unlike the typical “flu” that strikes the very young, chronically ill and elderly; this flu would attack and kill healthy young adults. ... reservoirs.[4,5] The common denominator in every influenza outbreak was its ability to follow the travel routes from city to city and sicken large numbers quickly and killing the very young and very old. ... virulence of a virus is determined by: the efficiency of the hemagglutinin ability to drift; functional ability of the nueraminidase, and the immunity of the host it infects to fight the virus. The...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects

Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"

... ophthalmology, dermatology, dentistry and rheumatology [10,11]. Based up on these data the aim of this study was to observe the potential of Esterified Hyaluronic Acid (EHA) as a coadjuvant of grafting ... Department of Dental Sciences and Surgery, University of Bari, Bari, Italy.  Correspondence to: Prof. F.R. GRASSI, Professor and Dean, Department of Dental Sciences and Surgery - University of Bari, ... AND METHODS Study drug Hyaloss® matrix, trade names of products composed entirely of an ester of hyaluronic acid with benzyl alcohol (HYAFF™) [2], a concentration rang-ing of from 20 to 60...
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Báo cáo Y học: Ruk is ubiquitinated but not degraded by the proteasome ppt

Báo cáo Y học: Ruk is ubiquitinated but not degraded by the proteasome ppt

... Ruk S retains only the C-terminal coiled-coil region.Although the precise role of this Ruk/CD2AP family isstill unknown, they are involved in the control of apoptosisand the regulation of cytoskeletal ... an inhibitory effect on the activity of PtdIns-3 kinase. The mechanism by whichPtdIns-3 kinase could be released from the inhibitorycomplex with Ruk L is still unknown. Ruk L polyubiquiti-nation ... initially stripped and reblocked prior toincubation with another type of primary antibody.Detection of ubiquitinated proteinsUb is highly conserved among eukaryotes, as only three of 76 amino...
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Báo cáo Y học: Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells pptx

Báo cáo Y học: Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells pptx

... how some of these interactions are affected by amutation in the SH2 domain of Shb, and consequently how the activation of JNK is affected.To further study the effects of the mutation in the ShbSH2 ... inproximity with the ZAP70 tyrosine kinase, the mainphosphate-donor and thus activator, of these signalingproteins. These interactions are then of importance for the activation of both the MAP kinase ... were synthesized. The peptides used in thispaper include: SLP -Y1 13: WSSFEEDDYESPND, SLP- Y1 28: QDGEDDGDYESPNE, SLP -Y1 45: APVEDDADYEPPPS, Vav -Y1 74: NEEAEGDEIYEDLMRL andVav -Y6 92: ILANRSDGTYLVRQRV,...
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Báo cáo Y học: A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus doc

Báo cáo Y học: A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus doc

... block by ikitoxin and birtoxincould be completely blocked by the addition of tetrodotoxin(Fig. 5). The similarity of this blocking pattern to effectsreported elsewhere suggests that binding of ... °C).Molecular modeling The SWISS-PDB VIEWERsoftware from the EXPASYserver(http://www.expasy.ch) was used to visualize and compare the effect of the substitution of a glutamic acid for a glycineon the ... concentrations of approximately 490 nMand 195 nM, respectively. Within 2–6 min thereafter(between the times marked ÔaÕ and ÔcÕ), the amplitude of the peak of the Na+current decreased. In the cells...
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Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx

Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx

... His92 actsas the general acid and Glu58 as the general base during the first step of the reaction. The hydrolysis of the cyclicderivative is performed by the same groups, but their rolesare ... by using the dinucleotide ApA as substrate [18]. Both mutant variantshydrolysed ApA. They displayed a K mvalue similar tothat of the wild-type protein although they exhibited alower catalytic ... for R121Q andR12 1K. Substitution of Arg121 by Lys or Gln abolishes the activity of a-sarcin to release the a-fragment from ribosomes. This lack of ribonuclease activity against the specific substrate...
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Tài liệu Báo cáo Y học: A novel meta-cleavage dioxygenase that cleaves a carboxyl-groupsubstituted 2-aminophenol Purification and characterization of 4-amino-3-hydroxybenzoate 2,3-dioxygenase from Bordetella sp. strain 10d doc

Tài liệu Báo cáo Y học: A novel meta-cleavage dioxygenase that cleaves a carboxyl-groupsubstituted 2-aminophenol Purification and characterization of 4-amino-3-hydroxybenzoate 2,3-dioxygenase from Bordetella sp. strain 10d doc

... purchased from TokyoKasei Kogyo (Tokyo, Japan), meat extract (ExtractEhlrich) was from Kyokuto Seiyaku Kogyo (Osaka, Japan)and 4-aminoresorcinol hydrochloride was from Aldrich(Milwaukee, Wis., ... dioxygenase;4-amino-3-hydroxybenzoate 2,3-dioxygenase.Dioxygenases catalyzing the fission of benzene rings are keyenzymes in the microbial metabolic pathways of aromaticcompounds. Most of these types of dioxygenases ... kDa. The N-terminalamino acid sequence of the enzyme was determined to beMIILENFKMPNVDLEAVMRYLXEEG.Identification of the reaction product The mass spectrum of the dimethyl ester of the enzymereaction...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ