... the one hand, PGE1 and PGE2reducedcGMP transport to only 57% and 59% of the con-trol value, and the inhibitory effect of dipyridamole and indomethacin was also less pronounced. On the other ... Wijnholds1,4 and Piet Borst11 Department of Molecular Biology, the Netherlands Cancer Institute, Amsterdam, the Netherlands2 Department of Pathology, Free University Medical Center, Amsterdam, the Netherlands3 ... 6-mercaptopurine and thioguanine, through the body. Active low-affinity,high-capacity efflux of these compounds and theirmetabolites from the erythrocyte by ABCC4 mightaffect the bioavailability of these...