Báo cáo khoa học: "THE EFFECTS OF INTERACTION ON SPOKEN DISCOURSE" potx
... hands -on assembly interactions, all interactive telephone teams produced a high and stable rate of con- firmations, with 18% of the total verbal inter- action spent eliciting and issuing confirmations, ... response times. In research on telephone conversations, transmission and access delays 2 of as little as .25 to 1.8 seconds have been found to disrupt the normal temporal...
Ngày tải lên: 31/03/2014, 18:20
... Neuregulin isoforms in dorsal root ganglion neurons: effects of the cytoplasmic domain on localization and membrane shedding of Nrg-1 type I. J Neurosci Res 84, 1–12. 34 Hu X, Hicks CW, He W, Wong P, ... (2008) Effects of neuron- specific ADAM10 modulation in an in vivo model of acute excytotoxic stress. Neuroscience 152, 459–468. 57 Nave KA & Salzer JL (2006) Axonal regulati...
Ngày tải lên: 16/03/2014, 04:20
... made contingent upon notification to the intelli- gence committee of the goals and risks of specific covert projects. 3. The action would provide only $19 million of the $50 million that ... information fields, each of which is stored on a stack. A set of rules is then applied to each entry on the stack, and assignment of each entry made Co one of the information c...
Ngày tải lên: 08/03/2014, 18:20
Báo cáo khoa học: The effect of heme on the conformational stability of micro-myoglobin doc
... native-like conformations. Conclusions The comparison of apo- and holo-lMb by MD simu- lations reveals a dramatic effect of the heme cofactor, which is seen to stabilize native Mb-like folded confor- mations ... During the simulations, the non-bonded interaction cut-off was set to 12 A ˚ , which is sufficiently large to include long-range elec- trostatic interactions. Main-chain hydrogen...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: The effect of pH on the initial rate kinetics of the dimeric biliverdin-IXa reductase from the cyanobacterium Synechocystis PCC6803 pptx
... were conducted within this range of enzyme concentration. In a preliminary set of experiments, there was no substrate inhibition up to a biliverdin concentration of 50 lm, in clear distinction to ... effect of pH on the kinetic parameters of a two-substrate enzyme, one substrate is held at 10 · K m (91% saturat- ing) and the variation of initial rate with the concen- tration of...
Ngày tải lên: 23/03/2014, 05:22
Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... evolutionary selection of protein sequences is the catalytic competence of the enzyme active site. The pre- cise orientation of the functional residues is maintained by a network of interactions ... enhancement of activity of 21.9-fold over the concentration range 2.5–40 lm, strongly sug- gesting that the loss of activity at low concentration may be attributed to subunit dissoci...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Inhibitory effects of nontoxic protein volvatoxin A1 on pore-forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic a-helix doc
... the membrane of cells. Inhibitory effects of VVA1 on the hemolytic and cytotoxic activity of VVA2 The effects of VVA1 on the hemolytic activity of VVA2 were studied by incubation of human red ... that this occurs via the interaction of one molecule of volvatoxin A1, which contains two amphipathic a-helices, with two molecules of volvatoxin A2, each of which conta...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts pptx
... ensure that the concentrations of ligands were maintained at a constant level during migration of the elongation factors, thereby favouring equilibrium conditions. The concentration of guanine nucleotides required ... containing different concentrations (20–60 l M )ofproline. Cloning of EF-Ts and construction of the EF-Ts mutant Wild-type E. coli EF-Ts was cloned into expression pla...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding affinity pptx
... cells. Selection of specific antigen binders To enrich phages displaying functional Fv, a round of biopanning was performed on immobilized antigen HEL. As many combinations of mutations on the conserved ... advantage of the spFv system over the conventional display system of monodomains on phage p3 was that it allowed simultaneous mutagenesis of V H and V L domains, and also...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Mutual effects of proton and sodium chloride on oxygenation of liganded human hemoglobin Oxygen affinities of the a and b subunits potx
... NaCl effects on HbA subunits oxygenation FEBS Journal 272 (2005) 6109–6119 ª 2005 The Authors Journal Compilation ª 2005 FEBS 6119 Mutual effects of proton and sodium chloride on oxygenation of ... different conformational forms of HbA is a key factor in the complete description of the sigmoidal be- havior of HbA oxygenation. Taking advantage of the photosensitivity of t...
Ngày tải lên: 16/03/2014, 14:20