Báo cáo khoa học: "The detection and representation of ambiguities of intension and description" pptx

... The detection and representation of ambiguities of intension and description Brenda Fawcett and Graeme Hirst Department of Computer Science University of Toronto Toronto, ... the beliefs of external agents. We propose that a unified approach to the representation of the alternative readings of intension- related ambiguities can be based on the notion o...

Ngày tải lên: 31/03/2014, 17:20

... of 1mm MgCl 2 and MnCl 2 were 410-fold lower and 1.6-fold higher than those of Tma-RNase HI. The K m values of Tma-CD determined in the presence of 1 mm MgCl 2 and MnCl 2 were 5.1- and 6.8-fold ... partial sequences of D13-R4-D12 (C) and R9-D9 (E) are indicated along the gel. (B, D, F) Schematic representation of the sites and extents of cleavage by various RNases...

Ngày tải lên: 06/03/2014, 22:21

... RMD monomer. The cofactor-binding domain and the substrate- binding domain are shown in aqua and light sand, respectively; the APPR portion of the cofactor (dark gray) and the ligand analog GDP- D- Man ... integration of the anomeric signals, the 4-keto and gem-diol forms of this compound coexist in equilibrium at an approximately 5 : 2 ratio. Full assignment of the NMR spectr...

Ngày tải lên: 16/03/2014, 01:20

... bioengineering using SBDs. One of the very obvious possibilities is the engineering of the size and properties of starch granules by overexpression of isolated SBDs, tandem repeats thereof, or SBD fusions with ... metabolism and structural characterization, and investigation of the thermodynamic fingerprint of a representative from this SBD group would advance our understandi...

Ngày tải lên: 30/03/2014, 01:20

... 177 and is involved in stabilizing strands b8 and b9. Ca4 is the weak binding site in PRK, which is formed by the side chain of Asp260 and the carbonyl oxygen of Thr16, and stabilizes the N- and ... VPRK and SPRK have an insert of three residues. Ca3 is the so-called strong bind- ing site found in PRK and formed by the side chain of Asp200 and the carbonyl oxygen atoms...

Ngày tải lên: 19/02/2014, 07:20

... regulators of responses to hypoxia [16] and embryological development of the central nervous system [17]. Many PAS domains bind cofactors or ligands, which are required for the detection of sensory ... binding of oxygen and other strong-field ligands. The heme domain permits kinase activity in the absence of bound ligand, but when the appropriate exogenous ligand is bound, this...

Ngày tải lên: 19/02/2014, 12:20

... wild-type and mutant P. ananatis GGPSs contained, in a final volume of 200 lL, 0.5 nmol of [1- 14 C]IPP (2 GBqÆmmol )1 ), 0.5 nmol of an allylic primer (GPP, FPP or GGPP), 1 lmol of MgCl 2 ,2lmol of ... made with type 1 FPSs from human [11] and pro- tozoa [6,12], and some of the structures [e.g. FPS from human (2F94 and 3B7L) and Trypanosoma brucei (2P1C and 2I19) bindi...

Ngày tải lên: 07/03/2014, 06:20

... are expressed in many cells of the seeds and developing seed pods. The A1 and A3 genes are expressed in the sepals and petals of flowers as well as the outer layer of the style, but are not expressed ... goal of understanding their function in the whole plant. Aspartic proteinases (EC 3.4.23) are one of the major classes of proteolytic enzymes found in plant and animal viru...

Ngày tải lên: 17/03/2014, 11:20

... N-myristoylation of GFP and DHFR fused to a myri- stoylation consensus motif. (A) Structures and N-terminal amino acid sequences of wild-type (wt) and G2A mutant forms of Myr– GFP and Myr–DHFR. ... of the expected size. The positions of pro- tein size standards are shown on the left of the gel. Table 1. Observed and calculated mass values for the tryptic N-terminal pepti...

Ngày tải lên: 29/03/2014, 21:20

... that the expression of the rat, mouse and human homologues of ERO1-Like protein a but not of the isoform ERO1-Lb are stimulated by hypoxia in rats vivo and in rat, mouse and human cell cultures. ... meaning of the oxygen regulation of ERO1-La expression likely is to maintain the transfer rate of oxidizing equivalents to PDI in situations of an altered cellular redox state...

Ngày tải lên: 31/03/2014, 01:20