... respectively, at 37.0 °C. This DNA cleavage was alargely exothermic reaction. The catalytic efficiency of BLM-A5 is of the same order of magnitude as that of lysozyme but several orders of magnitude ... activated BLM, is formed [2,4,5,13,14,16,18,46].Table 4. Comparison of the molar enthalpy change for the cleavage of calf thymus DNA induced by BLM-A5and those for the scission of calf thymusDNA ... number of experimental approacheshavebeenusedtoelucidatethemechanismofDNAcleavage by BLM in the past two decades [2–6,11–20],thermodynamic information for the scission, which is necessary for...