Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

... Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification Gyu Hyun Nam and Kwan Yong Choi National Research Laboratory of Protein ... structural features of TRAIL with those of two well-characterized TNF family proteins, TNF-a and LT, in their association with membranes upon acidification. In this stud...

Ngày tải lên: 31/03/2014, 08:20

8 369 0
Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"

Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"

... (1% tryptone, 1% NaCl, 0.5% yeast extract, w/v, pH 7.0) supple- mented with 80mg Kanamycin /l and cultured over- night at 37°C. Typically, 2mL of overnight grown culture was added to 200mL of ... filtration of GLP-1 through kidney [15]. Although structural modifica- tion of GLP-1 may overcome degradation by dipep- tidyl peptidase IV, this does not address the loss of GLP-1 by...

Ngày tải lên: 25/10/2012, 11:10

7 613 0
Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"

Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"

... that of unloaded erythrocytes (Table 4). Table 4, Erythrocyte osmotic fragility of unloaded eryth- rocytes and erythrocytes loaded with 8, 4 and 2 mg/ml pravastatin. Values are percent hemolysis ... in erythrocytes either by physical methods such as endocytosis and osmosis-based systems or by chemical perturbation of the erythrocytes membrane [16]. Endocytosis is the process...

Ngày tải lên: 25/10/2012, 11:10

9 829 0
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"

Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"

... atherosclerosis study. Conversely, Skogsberg et al. found a somewhat lower C allele frequency in their study with healthy young men from Sweden [9]. Treatment of obese rhesus monkeys with GW 501516, ... attributed the role of a master regulator of adipocyte differentiation. In contrast, the precise function of PPARδ is less well established. Treatment of obese rhesus monk...

Ngày tải lên: 31/10/2012, 17:03

4 568 0
Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx

Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx

... the secondary structure of a peptide consisting of residues 34–51 of HIV-1 Vpr. This part of Vpr plays an important role in Vpr oligomerization, contributes to cell cycle arrest activity, and is ... incorporation of Vpr. Keywords: HIV-1; Vpr; solution structure; dodecylphos- phocholine micelles; NMR. Human immunodeficiency virus type 1 (HIV-1) is a member of the lentivirus family...

Ngày tải lên: 24/03/2014, 04:21

6 401 0
Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

... wide variety of unrelated nascent polypeptides. These peptides usually show a high degree of hydrophobicity, which is consistent with the likelihood that BiP interacts with sequences normally located within ... necessary to the folding and oligomeric assembly of various glycoproteins [17]. To study the role of CNX and CRT in the folding of newly synthesized TSHR molecules, we pe...

Ngày tải lên: 31/03/2014, 08:20

8 444 0
Tài liệu Báo cáo khoa học: Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation doc

Tài liệu Báo cáo khoa học: Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation doc

... is directly phosphorylated by Mst2 kinase. Having confirmed the ability of Mst to phosphory- late Sav, we then examined what role, if any, that phosphorylation played in the ability of Mst to increase ... recently, Raf1 (with Mst2) [26]. The association of Mst with Nore1 or Rassf1 leads to an inhibition of Mst kinase activity, yet these complexes appear to mediate the pro-apoptoti...

Ngày tải lên: 19/02/2014, 06:20

13 321 0
Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling pdf

Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling pdf

... Department of Bioinformatics, Berlin-Buch, Germany; 2 Humboldt University Berlin, Institute of Biology, Berlin, Germany; 3 University of Maribor, Faculty of Education, Department of Physics, Maribor, ... absence of an exchange across the plasma membrane and of a n intrinsic dynamics of the IP 3 R [113]. In Ca cyt /protein models, the role of alternating supply and withdraw...

Ngày tải lên: 24/03/2014, 00:21

23 464 0
Báo cáo Y học: Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin Characterization of different PAI-1 mutants pdf

Báo cáo Y học: Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin Characterization of different PAI-1 mutants pdf

... demonstrated by Western blotting employing a polyclonal antibody (pAb) from chicken directed against human PAI-1 (a k ind gift of N . Grebenschikov, Institute of Ch emical Endocrinology, Uni- versity of ... amino-acid sequence analysis p erformed by TopLab (Martinsried, Germany) was used t o con®rm the identity of the puri®ed recombinant wild-type PAI-1 and wild-type PAI-2. Amidolyt...

Ngày tải lên: 31/03/2014, 15:20

9 295 0
Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"

Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"

... transferred with Smad5 and, possibly, with Smad1 but not with Smad8 [11, 13]. Compared with other BMPs, BMP9 uses a different type of receptor and signal transduction pathway, the details of which ... the results of a Western blot analysis of lysed Vero cells transduced with ADNULL, ADhBMP4, or ADrBMP4. The blot was tested with BMP4 antibody (Fig. 3A) and with β-a...

Ngày tải lên: 31/10/2012, 17:08

9 501 0
w