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Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

... Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor Sandrine Siffroi-Fernandez*, Annie Giraud, Jeanne Lanet and Jean-Louis ... coimmunoprecipitated with CNX and CRT than with BiP. Effects of interactions between TSHR and CNX and CRTWe then attempted to determine the effects of theseinteractions on the maturation of the receptor. ... from the association of the V2vasopressin receptor with calnexin (CNX) and calreticulin (CRT), and that of the gonadotropin receptor with thesetwo molecular chaperones and with GRP94 and BiP, which...
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Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"

... to Bonferoni and was seen only in subjects with a BMI below the median. Moreover, a significant association of the C-allele with coronary heart disease and BMI was obtained. Regarding the entire ... software. The association between the +294T/C polymorphism and serum lipids, coronary heart disease, and body mass index (BMI) was calculated using the Student’s t-test analysis with genotype as the ... obtained by Chen et al. [11], who studied 4 PPARδ haplotypes and found that effects on plasma lipids and coronary lesions were primarily due to the influence of the +T294C SNP. The C allele...
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Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

... analyses of TRAIL by CD spectroscopy The effects of acidification on the contents of secondarystructures in TRAIL were estimated by CD spectroscopy. The far-UV CD spectra of TRAIL at pH 7.0 and ... Meanwhile, the effect of zinc ions on the conformation of TRAIL at acidicpH was investigated by analyzing the CD spectra of TRAIL, as zinc ions were recently found to be important to the structure of ... Association of human tumor necrosis factor-related apoptosisinducing ligand with membrane upon acidificationGyu Hyun Nam and Kwan Yong ChoiNational Research Laboratory of Protein Folding and Engineering,...
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Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"

... pneumonia and early-onset VAP, defined as less than five days of mechanical ventilation and a Luna Clinical PulmonaryInfection Score of 5 or more [21]; the pooled analysisincluded only the subset ... subsequently identi-fied pathogens was beyond the scope of this economicanalysis and merits further evaluation. The lack of statistically significant between-group dif-ference in one of three ... intervention with a more rapid effect on VAP may allow patients to recover more quickly on the ward and to be discharged from the hospital morequickly. This hypothesis requires further evaluation with repeated...
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Báo cáo y học: "Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk – A Meta-Analysis"

... all of the items. Data extracted from these arti-cles included the first author’s name, year of publica-tion, country of origin, ethnicity, type of asthma, number of cases and controls, and the ... chronic inflammatory disorder of the airways and is characterized by variable airflow obstruction and bronchial hyper responsiveness (BHR) [1]. The prevalence and severity of asthma have been ... correlates with asthma severity [29]. Therefore, as one of the C-C chemokines, the RANTES polymorphisms necessarily resulted into the level of eosinophils elevating correspond, and then increased the...
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Báo cáo y học: " WT1 PEPTIDE VACCINATION IN COMBINATION WITH IMATINIB THERAPY FOR A PATIENT WITH CML IN THE CHRONIC PHASE"

... cessation of the peptides. An in vitro study as to the cytotoxicity of lymphocytes induced by mixed lymphocyte peptide culture demonstrated that cultured lymphocytes possessed cytotoxicity against ... [1]. Therefore, extermination of CML stem cells could be critically needed for CML patients to be fully liberated from the TKI therapy. On the other hand, anti-tumor cytotoxic T lympho-cytes ... wild-type WT1 peptides. By administration of WT1 peptides every two weeks in combination with the same amount of imatinib, the tendency of increase of bcr-abl transcripts was abrogated and the...
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Báo cáo y học: "Relationships between free radical levels during carotid endarterectomy and markers of arteriosclerotic disease"

... representation of the data. In the calculation of principal components, the components of the X-block that produce the strongest linear relation to the Y- variables are extracted. The principal ... 2-ethyl-3-hydroxy-2,4,4 trimethyloxazolidine (OXANOH) by gassing a 10 mM solution of the radical with hydrogen for 45 minutes in the presence of the catalyst platinum dioxide (PtO2). On contact ... conformational epitope in the apoB-100 moiety of LDL that is generated as a consequence of substitution of lysine residues of apoB-100 with malondialdehyde. The specificity for the antibody mAb-4E6 has...
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Báo cáo Y học: Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases pot

Báo cáo Y học: Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases pot

... Gershenzon, J., Konings, M. & Croteau, R.(1998) Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration of enzyme activities and their changes with development. ... Germany;3Laboratory of Plant Physiology, Wageningen University, the NetherlandsCitrus limon possesses a high content and large variety of monoterpenoids, especially in the glands of the fruit flavedo. The ... yet.Although the composition of lemon essential oil has hadconsiderable attention and enzymes responsible for the production of monoterpenes in the peel of lemon have beenpartially purified [18], their...
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Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx

Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx

... respond to the presence of IPTG, and s uch c lones were indeed found at a frequency of 22% of the second cross over event. Southern blot analysis and DNA s equencing of one of these clones in the ... easuring the e ect on DNA supercoiling of a reporter plasmid and on the expression of DNA gyrase. In a separate set of experi-ments the expression of DNA g yrase w as man ipulated and the control on ... counteract the effect of topoisomerase I and explain that supercoilingonly varied by 50% (Fig. 2). This lack of response of gyraseexpression to the modulation of the topoisomerase I activityimplies...
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Báo cáo y học: "A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv “Click Chemistry” targeted to αvβ3 integrin for therapy"

... nitriles 1 and 2 react with hydrazine to the 4-(6-(pyrimidine-2-yl)-1,4-dihydro- 1,2,4,5-tetrazine-3-yl)benzoic acid 3. Oxidation to 4 and reaction with thionyl chloride result in the corresponding ... 4) shows the DARinv reaction of the diaryl-tetrazine harbouring the 5-(dimethylamino)- naphthalene-1-s ul f on yl d y e 16 with cRGD functionalized with the Reppe Anhydride 14 to the product ... In flow cytometry, the increased relative amount of cells revealing granularity and the accession of the cell fraction featuring a clear augmentation of the g r a n u l a r i t y b o t h...
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