Báo cáo khoa học: Thioredoxin reductase from the malaria mosquito Anopheles gambiae Comparisons with the orthologous enzymes of Plasmodium falciparum and the human host pdf

... reductase from the malaria mosquito Anopheles gambiae Comparisons with the orthologous enzymes of Plasmodium falciparum and the human host Holger Bauer 1 , Stephan Gromer 1 , Andrea Urbani 2 , Martina ... AAB35418), and from the malaria parasite Plasmodium falciparum (PfTrxR-1, CAA60574). The enzyme of Anopheles shares 69%, 52%, and 45...

Ngày tải lên: 31/03/2014, 07:20

... interaction between the b8-strand of one monomer and the b6- and b7-strands of the other monomer. (B) Surface representation of the enzyme and view of the active site from outside. The active site ... underlined H and D residues in the first motif and the last H of the second motif are zinc binding ligands. Moreover, it has been proposed for other member...

Ngày tải lên: 15/03/2014, 11:20

... P10). The mean value of the diameter of inhibition zones and the deviation of three independent zones is given. D from mean gives the difference of the inhibition zones of a single strain from the ... case of the pksP mutant regardless of the car- bon sources the spores derived from. Interestingly, the wild type slightly altered the appearance of...

Ngày tải lên: 23/03/2014, 15:20

... (1) The parameters of these models are the distortion probabilities d(a j | a j−1 , j) and the translation prob- abilities t( f j | e a j ). The three models differ in their estimation of d, but the ... the same t. For further details of these models, the reader is referred to the original papers describ- ing them (Brown et al., 1993; Vogel et al., 1996). Let θ stand fo...

Ngày tải lên: 30/03/2014, 17:20

... the first hypothesis and therefore a direct involvement of PHI in electron transfer. This conclusion is consistent with the very low degree of identity between the N-terminal sequence of PHI and ... nm. N-terminal sequence The first 11 aminoacids at the N-terminus of PHI (sequence: SKVYLALQDND) were compared with the sequences of the so called ‘intermediate compo...

Ngày tải lên: 21/02/2014, 00:20

Ngày tải lên: 08/03/2014, 01:20

... daughters; the marking of certain nodes as dislocated; or the relocation of dislocated nodes to other positions within the tree. The content and ordering of phases is consistent with the syntac- tic theory ... compared with the work of Johnson (2002) and Dienes and Dubey (2003a) on WSJ. Valid comparisons exist for the insertion of uncoindexed empty nodes (C...

Ngày tải lên: 08/03/2014, 04:22

... concentration. In the insets a re reported linear replots of the slopes and of the intercept s of plot (A) vs. the r eciprocal of con centr atio ns of MTA. (B) Plo t of the reciproc al of initial velocity ... in the absence ( r)andinthepresenceof50l M (j )and2 00l M (m)ribose 1-phospate. In the insets are shown the replot s o f the slopes and the intercep...

Ngày tải lên: 16/03/2014, 18:20

... kDa) and bovine serum albumin (67 kDa) were deter- mined. A standard curve was made with the logarithm of the molecular mass of the proteins in the y-axis and the elu- tion volumes (V e ) in the ... consequence of the cooperativity toward aspartate and of the ordered binding of the substrates, first CP then aspartate [13]. These results raised the possibil...

Ngày tải lên: 16/03/2014, 19:20

... Analysis of the species generated during the activation process. The activation of PCPHa with LysC was performed in the conditions of Fig. 2B with the addition of the carboxypeptidase inhibitor from ... in the meth- ylotrophic yeast Pichia pastoris indicates both the suitability of this organism to host the heterologous expression of this class of enzy...

Ngày tải lên: 17/03/2014, 03:20