Báo cáo khoa học: Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities pptx
Tài liệu Báo cáo khoa học: Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat docx
... [21]. These considerations indirectly reinforce the argument that the basic domain should be exposed at the surface of the Tat-containing recombinant proteins and call other reasons to explain the ... in the internalization process [4]. Thus, steric hindrance of the heterologous protein itself could reduce the exposure of these shorter peptides to cellular structures, and...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: A new phospholipase A2 isolated from the sea anemone Urticina crassicornis – its primary structure and phylogenetic classification pptx
... annealing at the beginning and end of the cDNA and sequenced. Sequence analysis and homology modeling DNA and amino acid sequences were processed, analyzed and aligned with the vector nti software ... mammals and other vertebrates, it is less certain in the case of invertebrates and basal metazoans. Nevertheless, the amino acid sequence of the Sycon group I PLA 2 dem...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities pptx
... Biochem. 270) 3749 Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities Philippe ... CXC chemokines GCP-2 and ENA-78 by human gelatinase B, of human GCP-2 by neutrophil collagenase, and of the single mouse counterpart of...
Ngày tải lên: 31/03/2014, 07:20
Tài liệu Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway doc
... 30821065 and 30870559 from the China National Nature Sciences Foundation, 2006CB910703 from the Ministry of Sciences and Technology of China, and 07dz05907 from the Committee of Sciences and Technology ... one of the prodeath proteins in the Bcl-2 fam- ily, and interacts with prosurvival Bcl-2 family mem- bers to inactivate them [32]. Akt-1 phosphorylates Bad at Ser136, in...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... complex The interaction on the one hand between MT1-MMP and GRASP55 and on the other hand between GRASP55 and furin led us to hypothesize that GRASP55 could potentially play a role in the forma- tion ... the interaction between TGF-a ICD and the GRASP55 PDZ1 domain [37]. Phosphorylation has been found to modulate interactions between PDZ domains and their ligands [47...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx
... heterogeneous group of peptides with respect to their primary and secondary structures, their antimicrobial potentials, their effects on host cells, and the regulation of their expression. Most antimicrobial ... cells, keratinocytes, and epithelial cells. When released into the extracellular milieu, they exert their antimicrobial activity directly by attacking the microb...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Plasticity of S2–S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis pdf
... block the potential exosite and their removal starts the process of executioner caspase activation, as well as the expo- sure of the exosite. Clearly, further studies are required to identify the ... caspase-7. The peptide inhibitors make most of their contacts with the residues from the p10 subunit, except for those with the catalytic dyad (Cys186 and His144) and...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins ppt
... evaluated by the statistical potential used in the present study. In the case of the RNA muta- tions to the SRP complex, the mutated RNA residues are located in a double-stranded region of RNA, and do not ... onto the RNA bases nearest the center of the b-sheet structure of the RRM. We then scored these sequence-variant structures with the distance- dependent potential...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus – biochemical characterization and homology modeling doc
... of the program, setting the highest level of optimization. The quality of the mod- els and their stereochemical properties were analyzed using the programs procheck [65] and prosaii [66], and the best ... reference, the position of the sugar and of the metal in the crystallo- graphic template 1YOE. The two ligands were modelled in each binding site of SsCU-NH,...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: A novel tachykinin-related peptide receptor of Octopus vulgaris – evolutionary aspects of invertebrate tachykinin and tachykinin-related peptide ppt
... neuro- peptides such as the TK and TKRP family is correla- ted with the evolution and divergence of the nervous system and their biological roles, and thus, functional characterization of oct-TKs and oct-TKRPs ... oct-TKRPR, TKRPR and TKR family. The amino acid sequence of oct-TKRPR was aligned with those of the TKRPRs (UTKR, NKD, STKR, and DTKR), and TKRs (mouse...
Ngày tải lên: 19/02/2014, 00:20