Báo cáo khoa học: Interactions of the antimicrobial b-peptide b-17 with phospholipid vesicles differ from membrane interactions of magainins potx
Báo cáo khoa học: Interactions of the antimicrobial b-peptide b-17 with phospholipid vesicles differ from membrane interactions of magainins potx
... Interactions of the antimicrobial b-peptide b-17 with phospholipid vesicles differ from membrane interactions of magainins Raquel F. Epand 1 , Naoki Umezawa 2 , ... that there are differences in the manner in which b-17 affects membrane properties, compared with magainin. One manifestation of these differences is the lack of specificity of interact...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo khoa học: Apolipoprotein E-derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity pdf
... killing the bacterial cell. A further model proposes the forma- tion of pores formed by peptide aggregates, allowing entry of further peptides into the cell and interference with either protein synthesis ... substituted by another amino acid (but maintaining the naturally occurring distribution of cationic Arg and Lys residues within the sequence). Substitutions were made w...
Ngày tải lên: 30/03/2014, 03:20
Báo cáo khóa học: A new UV-B absorbing mycosporine with photo protective activity from the lichenized ascomycete Collema cristatum docx
... cultivation of mycobionts Mycobionts from Collema cristatum were obtained from the spores discharged from the apothecia of a thallus, and were Correspondence to M. Srebnik, Department of Medicinal ... absorp- tion maximum in the near ultraviolet region of the UV-A spectrum with a long tail extending into the infrared region. The two other UV absorbing compounds con...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... result from the different localization of these proteins in the cell. The molecular mechanisms underlying the transport processes of GPCRs from the ER to the cell surface have recently become the ... localization of these proteins in the cell rather than from the possible role of the D 2 R basic domain in the mechanism of D 1 –D 2 receptor heterodimerizat...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... to the susceptibility of E. coli model membranes to the action of AP1. An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of the individual membrane ... facili- tates their interaction with the anionic membranes of microbial cells, and they exert their antimicrobial action by the use of nonreceptor-based mecha...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx
... Fig. 4B for the 20- residue binding domain of the plasma membrane Ca 2+ pump ⁄ Ca 2+ -CaM complex, where the first 12 residues of the peptide are encompassed by the C-terminal end of Ca 2+ -CaM ... domain of nNOS. CaM is not only essential for the operation of nNOS and the other NOS isoforms, but is also the regulatory protein for a variety of other enzymes, inclu...
Ngày tải lên: 23/03/2014, 09:21
Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... reported to affect the normal trafficking of these proteins. The expression of the MT1-MMP AAA 573 mutant at the cell surface [18] could result from the intracellular traffic of MT1-MMP via an alternative ... with the PDZ2 domain of GRASP55. The interaction of PDZ domains with ICD internal motifs has previously been reported. For example, the interaction of th...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... bc 1 sub-complex, but the presence of only one of these two subunits does not substitute for the other. After the addition of ISP, the binding of the last subunit (i.e. Qcr10p) finally occurs. These find- ings ... not essential for the dimerization of the bc 1 complex, it is represented with dashed out- lines. The bc 1 complex apparently can dimerize without the ad...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... b3, b4 and b8 of the (b ⁄ a) 8 barrel domain, and for rBAT also with the short stretch near the C-terminus of domain B [9,19]. From the sequence–structure point of view, the basic difference between ... hcHATs, the regions of similarity cover the sequence segments within the C-terminal extracellular domain. The segments correspond, in fact, with some of the...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... illustrates the quality of the experimental data (Fig. 2B). Reconstruction of the overall shape of the PLDa2 from the X-ray scattering data was achieved by the ab initio modeling program dammin [24]. The ... deduced from these data. The binding event with the dissociation constant in the range of 0.1 mm might be associated with calcium binding to the C2 d...
Ngày tải lên: 19/02/2014, 02:20