Báo cáo khoa học: "Syntagmatic and Paradigmatic Representations of Term Variation" potx

... morphologi- cal, syntactic and semantic variations of multi-word terms is presented. It is applied to term normal- ization of French and English corpora in the medi- cal and agricultural domains. ... by a pair of such pairs: one of them is the source term (or normalized term) and the other one is the target term (or variant). The syntagmatic description of a t...

Ngày tải lên: 31/03/2014, 04:20

... Department of Biology and Biochemistry, University of Bath, UK 2 Department of Biochemistry, University of Wisconsin–Madison, USA 3 Department of Chemistry, University of Wisconsin–Madison, USA Introduction Upon ... studies of the structure and binding sites of enzymes. 8. Inhibitor binding to ribonucleases. J Mol Biol 45, 491–511. 33 Ui N (1971) Isoelectric points and c...

Ngày tải lên: 14/02/2014, 22:20

... structure of cN-II showing interfaces A and B and the Mg 2+ site. The inset shows the tertiary structure of each subunit. Effector sites 1 and 2 and the active site are shown. Table 2. Effect of point ... survival of several cell types. cN-II catalyses both the hydrolysis of nucleotides and transfer of their phosphate moiety to a nucleoside acceptor through formation of...

Ngày tải lên: 15/02/2014, 01:20

... is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9 and an a-helix from the C-terminus (Fig. 1A). The two subunits in the ... HPRT and hypoxanthine. (C) PRTFDC1 and guanine. (D) HPRT and guanine. Table 2. K m and V max values for Hx and G in the presence of 1 mM PRPP, determined using the DE-81 filt...

Ngày tải lên: 15/02/2014, 01:20

... performed using T-COFFEE [44]. Docking simulation of substrate on the active site of HYD Js The substrate binding pockets of HYD Js and the mode of interaction between substrate and enzyme were ... were also determined and compared. The specific activity of HYD Js was about three times higher than that of HYD Bp , and five times higher than that of HYD Pf (Table 1). As the...

Ngày tải lên: 18/02/2014, 08:20

... an accurate measure of the k off parameter in CaM-bound eNOS and nNOS [58], and thus prevented assessment of the relative importance of conformational change rates versus rates of FMNH 2 formation ... Model and simulations of cytochrome c reduction by NOS enzymes. (A) Scheme of cytochrome c reduction. The model uses four kinetic rates: dissociation (k 1 ) and association (...

Ngày tải lên: 18/02/2014, 11:20

... & Buckmann AF (1989) Enzymatic-synthesis of 4R-H-2NAD(P)H and 4S-H-2NAD(P)H and determination of the stereo- specificity of 7-alpha-hydroxysteroid and 12-alpha-hy- droxysteroid dehydrogenase. ... isotope effects using PEG-modified variants and glycoforms of glucose oxidase: the relationship of modification of the protein envelope to C–H activation and tunneling. Biochem...

Ngày tải lên: 18/02/2014, 11:20

... and pyridine nucleotides is highly dependent on the approach and colinear orientation of the N5 of the flavin, the hydride to be transferred, and C4 of the nicotinamide. In FNR, displacement of ... between unbound and sequentially PS I-bound polypeptides and correlated changes of the magnetic properties of the terminal iron sulfur clusters. J Mol Biol 327, 671–697. 13 Mu...

Ngày tải lên: 18/02/2014, 11:20

... D and E + F), (b) a few hydrogen bonds, and a hydrophobic interaction between A + C, B + E and D + F, and (c) electrostatic forces in the central channel of the hexamer between B, C and F, and ... and UDP, and ADP showed a rate that was > 20 times that of UDP. In order to determine the true K m for UMP and ATP, a two-substrate assay was performed at four concentration...

Ngày tải lên: 18/02/2014, 16:20

... is formed by an insertion of  230 residues (residues 133–367) between strands D and E and a smaller insertion of  50 residues (residues 404–458) between strands F and G. The hypervariable loop, Table ... vitro removal of the fiber protein from adenovir us requires the use of chaotropic salts and increased temperatures [32,33], and no release of fiber protein has been noted...

Ngày tải lên: 19/02/2014, 06:20