Báo cáo khoa học: "Syntagmatic and Paradigmatic Representations of Term Variation" potx
Báo cáo khoa học: "Syntagmatic and Paradigmatic Representations of Term Variation" potx
... morphologi-
cal, syntactic and semantic variations of multi-word
terms is presented. It is applied to term normal-
ization of French and English corpora in the medi-
cal and agricultural domains. ... by a pair of such pairs: one of
them is the source term (or normalized term) and
the other one is the target term (or variant).
The syntagmatic description of a t...
Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt
... Department of Biology and Biochemistry, University of Bath, UK
2 Department of Biochemistry, University of Wisconsin–Madison, USA
3 Department of Chemistry, University of Wisconsin–Madison, USA
Introduction
Upon ... studies of the structure
and binding sites of enzymes. 8. Inhibitor binding to
ribonucleases. J Mol Biol 45, 491–511.
33 Ui N (1971) Isoelectric points and c...
Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc
... structure of cN-II
showing interfaces A and B and the Mg
2+
site. The inset shows
the tertiary structure of each subunit. Effector sites 1 and 2 and
the active site are shown.
Table 2. Effect of point ... survival of several cell types. cN-II
catalyses both the hydrolysis of nucleotides and transfer of their phosphate
moiety to a nucleoside acceptor through formation of...
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... is mainly built
up by residues from the C-terminus and consists of a
two-stranded anti-parallel b-sheet composed of b2 and
b9 and an a-helix from the C-terminus (Fig. 1A). The
two subunits in the ... HPRT
and hypoxanthine. (C) PRTFDC1 and
guanine. (D) HPRT and guanine.
Table 2. K
m
and V
max
values for Hx and G in the presence of 1 mM PRPP, determined using the DE-81 filt...
Tài liệu Báo cáo khoa học: Isolation and molecular characterization of a novel D-hydantoinase from Jannaschia sp. CCS1 docx
... performed using
T-COFFEE [44].
Docking simulation of substrate on the active site
of HYD
Js
The substrate binding pockets of HYD
Js
and the mode of
interaction between substrate and enzyme were ... were also determined and
compared. The specific activity of HYD
Js
was about
three times higher than that of HYD
Bp
, and five times
higher than that of HYD
Pf
(Table 1). As the...
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf
... an
accurate measure of the k
off
parameter in CaM-bound
eNOS and nNOS [58], and thus prevented assessment
of the relative importance of conformational change
rates versus rates of FMNH
2
formation ... Model and simulations of cytochrome c reduction by NOS
enzymes. (A) Scheme of cytochrome c reduction. The model uses
four kinetic rates: dissociation (k
1
) and association (...
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling pptx
... & Buckmann
AF (1989) Enzymatic-synthesis of 4R-H-2NAD(P)H
and 4S-H-2NAD(P)H and determination of the stereo-
specificity of 7-alpha-hydroxysteroid and 12-alpha-hy-
droxysteroid dehydrogenase. ... isotope effects using PEG-modified
variants and glycoforms of glucose oxidase: the
relationship of modification of the protein envelope
to C–H activation and tunneling. Biochem...
Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: photosynthetic electron transfer from photosystem I to NADP+ doc
... and pyridine nucleotides is highly
dependent on the approach and colinear orientation
of the N5 of the flavin, the hydride to be transferred,
and C4 of the nicotinamide. In FNR, displacement
of ... between unbound and sequentially
PS I-bound polypeptides and correlated changes of the
magnetic properties of the terminal iron sulfur clusters.
J Mol Biol 327, 671–697.
13 Mu...
Tài liệu Báo cáo khoa học: Structural and functional investigations of Ureaplasma parvum UMP kinase – a potential antibacterial drug target ppt
... D and E + F), (b) a few hydrogen
bonds, and a hydrophobic interaction between A + C,
B + E and D + F, and (c) electrostatic forces in the
central channel of the hexamer between B, C and F,
and ... and UDP, and ADP showed a
rate that was > 20 times that of UDP.
In order to determine the true K
m
for UMP and ATP, a
two-substrate assay was performed at four concentration...
Tài liệu Báo cáo khoa học: Structural and biochemical characterization of a human adenovirus 2/12 penton base chimera pptx
... is formed by an insertion of 230 residues
(residues 133–367) between strands D and E and a
smaller insertion of 50 residues (residues 404–458)
between strands F and G. The hypervariable loop,
Table ... vitro
removal of the fiber protein from adenovir us requires the
use of chaotropic salts and increased temperatures [32,33],
and no release of fiber protein has been noted...
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