Báo cáo khoa học: Fidelity of hepatitis B virus polymerase pptx

... retroviruses. Keywords: HBV polymerase; HBV; fidelity; misinsertion; mispair; exonuclease. The hepatitis < /b> B virus (HBV) is a member of < /b> the hepadnavi- ridae, a family of < /b> enveloped hepatotropic DNA viruses. The virus ... infection remains to be elucidated, but the genetic variations of < /b> HBV are possibly related to the infidelity of < /b> the HBV polymerase and...

Ngày tải lên: 31/03/2014, 01:20

... a strong interaction between 2A2 mAb and cathepsin B. Determination of < /b> the 2A2 mAb binding site on cathepsin B The binding site of < /b> 2A2 mAb on cathepsin B was determined by SPOT analysis (SPOTs ... concentration of < /b> cathepsin B ⁄ 2A2 mAb complex. Lane 1, cathepsin B (CB); lane 2, cystatin C (CC); lane 3, 2A2 mAb (mAb); lane 4, CB ⁄ mAb (1 : 0.5); lane 5, CB ⁄ CC (...

Ngày tải lên: 18/02/2014, 11:20

... conducted in the absence of < /b> Tween 80. In contrast to the oxidation of < /b> this substrate by lignin peroxidase (LiP), oxidation of < /b> substrates by MnP did not proceed under anaerobic conditions. When ... quantitated by HPLC as described in the text and in the legend to Table 1. 286 G. V. B. Reddy et al. (Eur. J. Biochem. 270) Ó FEBS 2003 conducted in the absence of < /b> Tween...

Ngày tải lên: 20/02/2014, 23:20

... to aggregation but not to fibrils because of < /b> the lack of < /b> Ab central region. In the case of < /b> Tk-RNase HII m–n – Ab 10)24 , the proteins are not aggregated efficiently, because of < /b> the absence of < /b> an Ab C-terminal ... other Ab fragments, including full- length Ab. The two most abundant forms of < /b> Ab are the 40 and 42 residue peptides, Ab 1)40 and Ab 1)42 . Bot...

Ngày tải lên: 07/03/2014, 12:20

... (and a cysteine base), will also be able to isomerize All6P. SpRpiB and NaRpiB are unpublished structures described in the PDB as (putative) RpiBs. However, we are unaware of < /b> any biochemical data ... respectively Structured digital abstract l MINT-8081804, MINT-8081814: TcRpiB (uniprotkb:A1BTJ7)andTcRpiB (uniprotkb:A1BTJ7) bind ( MI:0407)by x-ray crystallography (MI:0114) Abbreviations...

Ngày tải lên: 15/03/2014, 00:20

... indicates the presence of < /b> immunoglobulins. Arrows indicate a single band (–EGF) or a doublet of < /b> bands (+EGF) that corresponds to the molecular mass of < /b> calpain B. These bands were excised, digested ... intact calpain B band, as described above. In a few experiments, the autolysis of < /b> radioactive [ 32 P]-labeled calpain B was also investigated by SDS ⁄ PAGE and t...

Ngày tải lên: 16/03/2014, 02:20

... the pool of < /b> soluble, potentially toxic Ab species. To investigate the disassembly of < /b> fibers, three separate preparations of < /b> preformed Ab40 and Ab42 fibers were incubated in the presence of < /b> varying ... allo-inositol are either inhibitors of < /b> oligomer formation or inhibitors of < /b> both oligomer and fiber formation. To differentiate between these two pos- sibil...

Ngày tải lên: 16/03/2014, 06:20

... 1 b OX110 · RA271 Yellow (whiA1/whiA + )18±3 b 47 ± 15 b Low 0.2 ± 0.05 b LU897 · LU898 White (whiA1/whiA1) 270 ± 25 b Not detectable b Not detectable 1.8 ± 0.2 b LU887 White (whiA1) 130 ± 16 b Not ... activity of < /b> PMLA and the efficiency of < /b> competition between PMLA and nucleic acids would both be influenced by the concentration of < /b> PMLA. An abnormal increase...

Ngày tải lên: 16/03/2014, 18:20

... serotypes, A and B, by agglutination reaction between heat-killed whole cells of < /b> C. albicans strains and rabbit anti-C. albicans whole cell sera of < /b> both serotypes absorbed with whole cells of < /b> another ... 4.147 Manb1fi2Manb1fi2Manb1fi2Mana1fi2 1.9 24 4.844 4.247 Manb1fi2Manb1fi2Manb1fi2Mana1fi2 1.9 25 4.857 4.263 Manb1fi2Manb1fi2Mana1fi2 11.7 26 4.849 4.269 Manb1fi2Manb1fi2Mana1fi30 27...

Ngày tải lên: 17/03/2014, 03:20

... length of < /b> IFN -b mRNA was analysed by Northern blot, using a 32 P-labelled antisense IFN -b riboprobe. As a control, the membrane was hybridized with a GAPDH antisense riboprobe. (C) Total RNA of < /b> cells ... contained 10 lgofRNA (between 10–100 ng of < /b> the in vitro transcribed mRNA supplemented by a carrier tRNA) and 10 lL of < /b> lipofectine in a total volume of < /b> 2...

Ngày tải lên: 17/03/2014, 10:20