Báo cáo khoa học: Acylation of lysophosphatidylcholine plays a key role in the response of monocytes to lipopolysaccharide ppt

... cells. Taken together, the data from these studies suggest that LPCAT is a key enzyme in both the pathways of activation (priming) and the in ammatory response to LPS in monocytes. Keywords: lysophosphatidylcholine ... lysophosphatidylcholine acyltransferase; lyso- phosphosphatidate acyltransferase; in ammatory response; lipopolysaccharide. Endotoxin, the lip...

Ngày tải lên: 31/03/2014, 01:20

... directly involved in interdomain communication. This data can be reconciled with an atomic- scale model of human ABCB1. Taken together, these results indicate that TM12 plays a key role in the progression ... progression of the ATP hydrolytic cycle in ABCB1 and, in particular, in coordinating conformational changes between the NBDs and transmembrane domains. Abbrev...

Ngày tải lên: 06/03/2014, 22:21

... have therefore measured the thermodynamic parameters of RNase -A in the presence of these amino acids and amino acid derivatives, and values of DG D °, measured in triplicate, are given in Table ... polyhydric alcohols (sorbitol, glycerol, xylitol, adonitol, mannitol) and amino acids and derivatives (glycine, alanine, proline, serine, lysine, b-alanine and taurine) that have...

Ngày tải lên: 07/03/2014, 00:20

... noted (Halliday and Hasan, 1976, inter alia) that it is the main verb do that is operative in these forms of anaphora, in contrast to the auxiliary do operative in VP-ellipsis/ It is the pronoun ... this aspect was crucial for handling the gapping data, since the infelicity of gapping in non-parallel constructions hinged on there no longer being a propositiona...

Ngày tải lên: 08/03/2014, 07:20

... membrane relative to that in the total cell lysate was calculated. Data are the average of two independent experiments. The percentage immature NCT level in the cell membrane relative to that in the ... Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT et al. (2003) APH-1 interacts with mature and immature forms of presenilins and nicastrin and may pla...

Ngày tải lên: 23/03/2014, 04:20

... accounts for at least 2.5% of the total cell protein of A. profundus indicating an important catabolic function. In analogy to the Mvh:Hdr complex from Methanothermobacter species, the A. profundus enzyme ... run into the gel (lane 2). This behaviour is typical for integral membrane proteins. Table 1. Amino-terminal sequences of the membrane-bound heme containing enzyme...

Ngày tải lên: 30/03/2014, 13:20

... evaluation model for statistical syntactic parsing Given a sentence, the task of statistical syntactic parsing is to assign a probability to each candidate parsing tree that conforms to the grammar ... the estimation of P ( T|S ). In the syntactic parsing model which uses rule- based grammar, the probability of a parsing tree can be defined as the probability...

Ngày tải lên: 20/02/2014, 18:20

... structure of the Phe35fiTyr mutant shows that the hydroxyl oxygen atom of the side chain of Tyr35 is 3.21 A ˚ away from the atom CHB of the pyrrole group of the heme, making strong van der Waals’ contacts ... treated as a first-order reaction. The kinetic trace can be described mathematically by the equation DA t ¼ DA eq (1–e –kt )whereDA t is the increase in a...

Ngày tải lên: 08/03/2014, 10:20

... FEBS executing the terminal stage of a myriad of signaling cascades that initiate at the cell surface and reach their climax in the nucleus [8–10]. Upon activation by mitogen-activated protein kinas- es, ... change in thermal power as a function of each injection was automatically recorded using origin software and the raw data were further processed to yield binding i...

Ngày tải lên: 22/03/2014, 16:20

... on the top of each lane indicate the time of digestion in min. Samples were run on (A) a 15% SDS ⁄ PAGE, or (B) a 17.5% SDS ⁄ PAGE. (C) A densitometric scan of the above bands showing the amount ... through the interactions of the DnaK–DnaJ–GrpE machinery and by HflB-mediated degradation. Interestingly, these latter proteins that promote the degradation of r 32...

Ngày tải lên: 23/03/2014, 10:20