Báo cáo khoa học: Tracking interactions that stabilize the dimer structure of starch phosphorylase from Corynebacterium callunae Roles of Arg234 and Arg242 revealed by sequence analysis and site-directed mutagenesis doc

... 2003 Tracking interactions that stabilize the dimer structure of starch phosphorylase from Corynebacterium callunae Roles of Arg234 and Arg242 revealed by sequence analysis and site-directed mutagenesis Richard ... structure. The results have revealed clearly that Arg234 and Arg242 of the TOWER interface region of StP partia...

Ngày tải lên: 31/03/2014, 01:20

... represents the impact of the piece of evidence on the subsets of O. A bpa assigns a number in the range [0,1] to each subset of O such that the numbers sum to 1. The number assigned to the subset ... without cues. Furthermore, substantial improve- ment is gained by the use of counters since they prevent the effect of the "exceptions of the rules...

Ngày tải lên: 17/03/2014, 23:20

... in the K i by DS, and no effect on K i by Ch6S (Table 2). The various effects of sulfated polysaccharides on inhibi- tion of elastase-2 by eglin c and by the tetrapeptide derived from his sequence ... in the absence or presence of effectors, not to determine absolute values from their dependence on the concentration of eglin c and a 1 -PI. The effects...

Ngày tải lên: 16/02/2014, 14:20

... the steroid output of the adrenal. The discovery that the two CYP17 isoforms are two genes and that the genotypes differ not only by the genes present, but also by the copy number, suggests that ... to identify the distribution of the two CYP17 alleles in the South African Angora population. These data revealed that the two CYP17 isoforms were not th...

Ngày tải lên: 07/03/2014, 06:20

... indicate that the banded fibril forming collagens are traversed specifically near their ÔdÕ bands, within the gap region of the collagen fibrils, by the filamentous beaded structures of the type ... without the addition of complexes were performed. For the analysis of interactions between proteoglycans and collagens, the sensograms were corrected by a modificati...

Ngày tải lên: 07/03/2014, 16:20

... [4]. Other key attributes of the catalytically competent structure are the ‘oxyanion hole’ formed by the amide nitrogens of Ser195 and Gly193, and substrate-binding subsites (S1, S2, S3, and S4), ... chains of the catalytic triad residues (Asp102, His57, and Ser195) are indicated (yellow for ‘open’; magenta for ‘closed’), as is that of the 220-loop residues 215...

Ngày tải lên: 15/03/2014, 11:20

... calculations The netropsin amidinium end The contact area of the Nt amidinium end (NAE) was investigated by evaluating the interaction energies and hydrogen positions of the end fragment and the bases of ... of van der Waals’ interactions between the drug and the floor and walls of the minor groove [21,22]. Electrostatic interactions between the nega...

Ngày tải lên: 16/03/2014, 22:20

... by cleavage between the methylthio-substituted carbons. They clearly showed that the two species of monoeno- ates formed by the partial hydrogenation of the unknown fatty acid were 16:1 D-7 and ... acid methyl esters pre- pared from the triacylglycerol fraction of the cells were analyzed by GC. The number at the top of the peak on the chromatogram cor-...

Ngày tải lên: 23/03/2014, 09:20

... stopped by the addition of 2 mL of chloroform ⁄ meth- anol (2 : 1, v ⁄ v) and 500 lL of water. The formed products were extracted and analyzed as described above. Statistical analysis The level of ... in the de novo synthesis of a given phospholipid, including PI. Hence, the rate of synthesis and the amount of CDP-DAG molecules that were used as substrate...

Ngày tải lên: 29/03/2014, 22:21

... likely that ubc9 and the UFD of uba2 interact at the a1 region. (b) The region below the a1 helix consists mainly of the N-terminal exten- sion of a1 and loops between the b2 and b3 strands and the ... E1 is composed of APPBP1 (APP binding protein 1) and uba3. The domain structures of Aos1 and APPBP1 resemble the N-termini, and those of uba2 and...

Ngày tải lên: 30/03/2014, 04:20