Báo cáo khoa học: Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase A theoretical study using elementary flux modes Stefan Schuster and Dimitar Kenanov ppt

... Journal 272 (2005) 5278–5290 ª 2005 FEBS Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase A theoretical study using elementary flux modes Stefan ... synthesis of ATP is possible. As for pathways using adenosine, a straightforward assumption is that these pathways start with adenosine...

Ngày tải lên: 30/03/2014, 20:20

... suspended in the medium containing 250 mm sucrose and 5 mm Tris (pH 7.3). Protein was estimated according to Bradford [39] using BSA as the standard. Measurement of respiration and membrane potential Prior ... [29,30]. Bimodulular kinetic analysis of the effects of Cd 2+ and Cu 2+ ions on oxidative phosphorylation The data in Figs 2 and 3 indicate that Cd 2+ and...

Ngày tải lên: 16/03/2014, 02:20

... evaluation model for statistical syntactic parsing Given a sentence, the task of statistical syntactic parsing is to assign a probability to each candidate parsing tree that conforms to the grammar ... Predictive information redundancy can be used as a measure of the redundancy between the predictive information of a feature type and that of a feature type combinat...

Ngày tải lên: 20/02/2014, 18:20

... evaluated on a long-lasting and functional basis, rather than on an acute and his- tological basis. Also, careful and rigorous selection of patients with salvageable tissue [evidenced using mag- netic ... Italy Therapeutic strategies aimed at reducing brain dam- age after ischemic stroke have been a major focus of academic and industrial research for the past 30 years. Two...

Ngày tải lên: 07/03/2014, 03:20

... [30,36,41,42]. In contrast, the excellent Table 1. Values of kinetic and thermodynamic parameters for cyanide binding to ferric and ferrous heme-proteins. Values in italic were cal- culated according to the ... displays the highest affinity as well as the fastest combination and the slowest dissociation rate for cyanide binding of the known members of the Hb super...

Ngày tải lên: 16/03/2014, 06:20

... FEBS executing the terminal stage of a myriad of signaling cascades that initiate at the cell surface and reach their climax in the nucleus [8–10]. Upon activation by mitogen-activated protein kinas- es, ... domains containing Trx-tag at the N-terminus and His-tag at the C-terminus. Addition- ally, titration of a protein construct containing thioredoxin with a C-te...

Ngày tải lên: 22/03/2014, 16:20

... through the interactions of the DnaK–DnaJ–GrpE machinery and by HflB-mediated degradation. Interestingly, these latter proteins that promote the degradation of r 32 are themselves pro- duced as a result ... binding, 5% of the input solution was kept aside separately and was used as a control for comparison. The proteins were analyzed in an 11% SDS ⁄ PAGE and by west...

Ngày tải lên: 23/03/2014, 10:20

... Panel on Euthanasia of the AVMA and in compliance with the CINVESTAV and Trudeau Institute IACUC guidelines. The IL-3 dependent murine pro-B cell line, Ba/F3 (a generous gift from D. Campana, ... °C. The cells were analyzed by cytometry using a FACSCalibur (Becton-Dickinson, San Jose, CA, USA). Surface biotinylation of proteins To analyze the stability of CD38 on t...

Ngày tải lên: 23/03/2014, 12:20

... self-cleavage kinetics of ADHR1 are independent of the order of addition of the cofactors adenine and Mg 2+ . The kinetics of self-cleavage of ADHR1 were analyzed after 10 min of preincu- bation ... showed that the specificity of adenine in restoring the catalytic activity of ADHR1 is rather loose [16], and that some adenine analogs, such as 6-methyladen...

Ngày tải lên: 07/03/2014, 00:20

... nuclear factor kappaB activity and are independent of the B-Raf ⁄ mitogen-acti- vated ⁄ extracellular signal-regulated protein kinase path- way and the Akt pathway. Cancer 104, 879–890. 26 Takada ... MAPK signaling pathways of p38 MAPK and ERK1⁄ 2. The simultaneous activation of both MAPK pathways is indicated by the similar time dependence in the activa- tion of...

Ngày tải lên: 07/03/2014, 12:20