Báo cáo khoa học: Two different types of hepcidins from the Japanese flounder Paralichthys olivaceus ppt

... is different from that of human, mouse and other reported fish hepcidins. In liver, some cells expressed both types of hepcidins, while other cells expressed only one of them or neither of them (Fig. ... winter flounder, Pseudopleuronectes americanus has three different types of hepcidin [11]. The gene expressions of three types of hepcidins in dif- ferent org...

Ngày tải lên: 30/03/2014, 20:20

... more complete picture of the bio- chemical outcome of these point mutations. Results The effect of chaperonin on the ability of the mutant proteins to fold For a number of other MCAD point mutations, co-overexpression ... present on the west- ern blot and by the minimal effect of chaperonin (Fig. 1B). This suggests that the R256T mutation harms the function of t...

Ngày tải lên: 20/02/2014, 02:21

Ngày tải lên: 18/03/2014, 02:20

... binding governs the different roles of UQ 10 at the Q A and Q B sites. However, the molecular origin of the strong binding of the 4C¼O group is not clear. The conformation of the C(5) and C(6) ... group and the oxygen at C4 lower the binding order of the carbon C4 and strengthen the downshift of the 4C¼O mode [10,11]. In principle, X-ray-based structural...

Ngày tải lên: 23/03/2014, 21:20

... The homopentameric B-subunits of these toxins (STxB) bind to 10–15 mole- cules of Gb 3 at the plasma membrane [12] and allow the intracellular transport of the holotoxin and the delivery of the ... to the TGN and the ER, endocytosis of STxB was not inhibited in the recovery condition (Fig. 6A), and neither was that of transferrin (Tf) (Fig. 6B). These results doc...

Ngày tải lên: 30/03/2014, 10:20

... In this case the structural differences are related to the sequence diversity rather than the number of residues. Analysis of the surface features of a-conotoxins reveals the fact that the cysteine ... X n refer to the number of noncysteine residues), where the loops correspond to the residues between successive cysteine residues. The number of residues in the...

Ngày tải lên: 19/02/2014, 12:20

... observations of the monomeric form of DePsipher in the autophagosome together, the mito- chondria taken in the autophagosome might be broken, once they were incorporated into the autophagosomes. These ... green with AO (Fig. 2). The localization of the acidic organelles (Fig. 2) is clearly different in distribution and in num- ber from that of the green fluorescent...

Ngày tải lên: 20/02/2014, 03:20

... are required for the synthesis, maturation and export of the two ribosomal subunits [1]. Most of the constitu- ents of the preribosomal particles have been identified in yeast by exploiting the potent ... Alternatively, they may be required for the more complex regulation of eukaryotic protein synthesis [9]. The identification of the role of a specific RP is com- pl...

Ngày tải lên: 07/03/2014, 01:20

... speci- ficity of CPO has been proposed to be a result of the presence of a basic residue at the substrate rec- ognition pocket [5,37], which is different than those for the other two general types (A ... isolated from marine invertebrates, and in not one case have the whole or extended sequences been disclosed. This would be the case for the two CPAs and CPBs isolat...

Ngày tải lên: 07/03/2014, 02:20

... idescribes the current state of the S~/~gYN project , whose goal is be develop a module for generation of German from a semantic representation. The first application of this module is within the ... titles of Japanese papers from the field of "Information Technology". This material comes from Japanese documentation data bases and contains in ad...

Ngày tải lên: 08/03/2014, 18:20