Báo cáo khoa học: Megalin binds and mediates cellular internalization of folate binding protein potx
Báo cáo khoa học: Megalin binds and mediates cellular internalization of folate binding protein potx
... Megalin binds and mediates cellular internalization of
folate binding protein
Henrik Birn
1
, Xiaoyue Zhai
1
, Jan Holm
2
, Steen I. Hansen
2
, Christian Jacobsen
3
, Erik I. Christensen
1
and ... number of
vitamin carrier proteins [18], including retinol binding
protein [19], transcobalamin [20], and vitamin D
binding protein [21,22] and its role for the r...
Báo cáo khóa học: Genetic approaches to the cellular functions of polyamines in mammals potx
... inadequate
synthesis of nucleic acids and proteins in the absence of the
polyamines – or, in the case of ODC deficiency, an excessive
accumulation of decarboxylated AdoMet – inhibiting DNA
methylation and thus ... synergism between
the polymorphism of the ODC gene and the use of aspirin
was proposed to be a combined result of an inhibition of
polyamine biosynthesis and...
Báo cáo khoa học: Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73c in lung cancer doc
... TA
isoform(s) and the antiapoptotic DM isoforms. In gen-
eral, TAp73 isoforms regulate the transcription of
DMp73 isoforms, which, in turn, act as dominant nega-
tive regulators of both TAp73 and ... Programme, Division of Surgery and Oncology, University of Liverpool Cancer Research Centre,
University of Liverpool, UK
5 Laboratory of Clinical Virology, Faculty of Medicine...
Tài liệu Báo cáo khoa học: Guanidinium chloride- and urea-induced unfolding of FprA, a mycobacterium NADPH-ferredoxin reductase Stabilization of an apo-protein by GdmCl docx
... measure of the conformational stability of
the protein [1,2]. Protein unfolding ⁄ folding studies in
GdmCl and urea solutions have focussed on the identi-
fication of equilibrium and kinetic intermediates ... concentration of about 0.8 m, stabilization of
apo -protein was observed. The stabilization of apo-FprA by guanidinium
chloride is probably the result of direct bi...
Tài liệu Báo cáo khoa học: Dimer asymmetry and the catalytic cycle of alkaline phosphatase from Escherichia coli doc
... during metal-ion binding,
positive for the binding of Zn
2+
to the M1 site, and
negative for the binding of the activating cations to the M3
site [5,6]. Phosphomonoester hydrolysis and transphos-
phorylation, ... form of a dianion [9],
however, the slow dissociation of P
i
,andtheslow
phosphorylation of Ser102 by P
i
, are both in accordance
with P
i
binding in form of...
Báo cáo khoa học: Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN ppt
... against S6 and
the GST-tag. (C) Immunoblot analysis of the
phosphorylation status of p70S6K and S6 in
Paskin
+ ⁄ +
and Paskin
) ⁄ )
MEFs. (D) Immu-
noblot analysis of the phosphorylation status
of p70S6K ... addresses
Division of Digestive and Liver Diseases,
Department of Medicine, Columbia
University, New York, NY, USA
àInstitute of Cell Biology, ETH Zu
¨
rich,
Switze...
Báo cáo khóa học: O-acetylation and de-O-acetylation of sialic acids in human colorectal carcinoma docx
... bovine submandibular gland mucins as described by
Reuter and Schauer [23].
4
Preparation of lysosomal, microsomal and cytosolic
fractions from human colonic mucosa
The lysosomes, microsomes and cytosol ... Fluorometric-HPLC and GC-MS analysis of glycoconjugate-bound and free sialic acids isolated from the mucosa of matched resection margin and colorectal carcinoma tissue. Si...
Báo cáo khoa học: Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses ppt
... A and B box sequences known to be involved in
NTP binding and hydrolysis [12]. Crystal structures of the
SF1 DNA NTPase/helicases from Escherichia coli and
Bacillus stearothermophilus, and of ... identification of these proteins as BSA and WNV
NTPase/helicase (Fig. 1, lane 2) [20].
Protein concentrations of preparations of the NTPase/
helicases were determined by SDS/PA...
Báo cáo khoa học: "A Comparison and Semi-Quantitative Analysis of Words and Character-Bigrams as Features in Chinese Text Categorization" potx
... as-
pects of IR and TC. So it is significant to make a
detailed comparison and analysis here on the
relative value of words and bigrams as features
in Text Categorization. The organization of this ... proportion of 2:1
into a training set and a test set. Every document
has the full-text and has been entirely word-
segmented
7
by hand (which could be regarded as
a gold...
Báo cáo khoa học: "LEXICON-GRAMMAR AND THE SYNTACTIC ANALYSIS OF FRENCH" pot
... of French verbs have been limited in
terms of the size of sentences, that is, by restricting the type of
complements to object complements. We considered 3 main types of
objects: direct, and ... the intersection of the corresponding row and column,
if not s "-" sagn. The description of the French verbs does not
have the shape of a 10,000x500 matrix. Because...