Báo cáo khoa học: The light-harvesting antenna of the diatom Phaeodactylum tricornutum Evidence for a diadinoxanthin-binding subcomplex doc

Tài liệu Báo cáo khoa học: Insulin-dependent phosphorylation of DPP IV in liver Evidence for a role of compartmentalized c-Src ppt

Tài liệu Báo cáo khoa học: Insulin-dependent phosphorylation of DPP IV in liver Evidence for a role of compartmentalized c-Src ppt

... supported by the Natural Sciences and Engineering Research Council (NSERC) of Canada (RF: OGPO157551), by the Canadian Diabetes Associ- ation (CDA) and a grant from the Fondation pour la Recherche ... that the luminal domain of DPP IV carries dominant apical sorting information while the short cytoplasmic tail and the transmembrane domain contain competing basolateral sortin...

Ngày tải lên: 19/02/2014, 07:20

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Báo cáo khoa học: Genome-wide analysis of clustering patterns and flanking characteristics for plant microRNA genes doc

Báo cáo khoa học: Genome-wide analysis of clustering patterns and flanking characteristics for plant microRNA genes doc

... larger) than the average distances of miRNA pairs to evaluate the statistical significance for clustering patterns in the four plant species. Prediction of the core promoter of the plant miRNA ... of known miRNAs are arranged in clusters. For example, 48% of human miRNAs appear as clusters within a maximum inter-miRNA distance of 10 kb [21] and 50% of miRNAs appea...

Ngày tải lên: 28/03/2014, 23:20

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Báo cáo khoa học: The light-harvesting antenna of the diatom Phaeodactylum tricornutum Evidence for a diadinoxanthin-binding subcomplex doc

Báo cáo khoa học: The light-harvesting antenna of the diatom Phaeodactylum tricornutum Evidence for a diadinoxanthin-binding subcomplex doc

... diatoms, DD and DT are mainly associated with the FCP antenna [12], but their exact localization in the different subfractions of the antenna has not yet been determined. Therefore, the aim of ... differs in many aspects from that of green plants and algae. There are no grana stacking and no segregation of the photosystems [18]. The main components of the antenna...

Ngày tải lên: 30/03/2014, 20:20

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Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt

Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt

... possibly of other Meis paralogs, may play a role in regulating transcriptional activity, but it appears that the Hth domain does not maintain the cytoplasmic localization of Prep1. Additionally, the greatest ... if interaction of Pbx1 with the Hth domain altered the conformation or intramolecular interactions, allowing access to the AD. As the autoinhibition affected an...

Ngày tải lên: 16/02/2014, 15:20

14 753 0
Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

... the global optimum. As there are many random steps involved, the algorithm can traverse the multidimensional parameter landscape in an infinite number of ways, at least in a practical sense. The ... property and size of an amino acid residue could affect the protein negatively. The novel variables, the calculated energy for a spe- cific residue exchange and for the a...

Ngày tải lên: 18/02/2014, 11:20

14 562 0
Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc

Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc

... GCA CAC TAT ATT AAA CGG CAA AGC CGT AAA ACC CC G TGT AGG CTG GAG CTG CTT CG- 3¢) and rluD114::cat(pKD3) 3¢ (5¢-GAC CAG ATT AAT GTG AAA AGA AAA TCA CGC GTA CCG GAT CGT CTT G AT GGG AAT TAG CCA ... to the RluA family [2]. Binding of RluA to one of its substrates, tRNA Phe anticodon stem-loop, induces reorganization of the RNA [21]. An ability of the RNA substrate to adopt the al...

Ngày tải lên: 18/02/2014, 16:20

8 597 0
Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx

Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx

... molecule, and individual mutations drastically reduced the activity. Because Ala lacks the character- istic side chains of Glu and Arg, the mutant recep- tors are devoid of the functional groups at the particular ... l M) for the basal constitutive activity, and the inverse antagonist activity of BPA (1 and 10 l M) against the inverse agonist activity of 4-OHT (1 and...

Ngày tải lên: 18/02/2014, 16:20

12 583 0
Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt

Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt

... pep- tide variants of IA 3 ; and to Doug Lamont and Kenny Beattie, University of Dundee, for carrying out mul- tiple mass spectrometry analyses of the IA 3 variants. The endless patience, tolerance and ... inhibitors of aspartic proteinases are rather rare in nature. Thus, there is a need to under- stand the mechanisms of action of the few that are known, in order to e...

Ngày tải lên: 19/02/2014, 00:20

10 510 0
Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

... located at the interface between the N-terminal and the C-terminal a- helices, indicated Fig. 5. Thermal stability of the A- state of cytochrome c as a func- tion of sulfate concentration. Sulfate ... the sulfate-induced destabilization of the HS acid-denatured form, with further formation of the LS (I HH ) A- state; (b) for the slow phase, to formation of...

Ngày tải lên: 19/02/2014, 05:20

11 487 0
Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-fin eelpout, Zoarces elongatus Kner ppt

Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-fin eelpout, Zoarces elongatus Kner ppt

... mm of nfeAFP8. These data indicate that ‘less active’ AFP isoforms can exert a substantial level of antifreeze activity after the addition of a small amount of ‘active’ isoform. The less active ... clear concentration dependence on, the addition of a small amount of a QAE1 isoform, nfeAFP8 (Fig. 7). This is similar to the case of the QAE2 isoform, nfeAFP13; th...

Ngày tải lên: 19/02/2014, 16:20

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