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Báo cáo khoa học: Selenium affects biosilica formation in the demosponge Suberites domuncula Effect on gene expression and spicule formation pot

Báo cáo khoa học: Selenium affects biosilica formation in the demosponge Suberites domuncula Effect on gene expression and spicule formation pot

Báo cáo khoa học: Selenium affects biosilica formation in the demosponge Suberites domuncula Effect on gene expression and spicule formation pot

... formation in sponges and in turn skeleton formation in these animals. The final interesting finding for the biotechnologicalapplication of silicatein, especially with respect to the understanding ... immunoblot. Gene expression studies The effect of selenium on the expression of the genesencoding selenoprotein M, spicule- associated protein, and silicatein was studied (Fig. 8). In the absence ... selenium on spicule formation FEBS Journal 272 (2005) 3838–3852 ª 2005 FEBS 3841 the amino acids glutamine, lysine and histidine at the N-terminus and the nonpolar amino acid proline and the hydroxy...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... at longer incubationperiods. Interestingly, the interruption of TAG synthe-sis preceded the appearance of toxic effects, supporting the notion that it constitutes the initiating event in the process ... responsecan be divided in two phases according to the intensity and the duration of the stress. An initial adaptiveresponse culminates in the temporary inhibition ofprotein synthesis, providing ... 4A), indicating the initiation of ERstress-induced apoptosis. Oleate was unable to induce the expression of the proapoptotic protein CHOP, and its coadministration with stearate inhibited CHOPexpression...
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Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx

Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx

... intermediate;V, aminoquinol intermediate. In the oxidative half-reaction the ami-noquinol intermediate is converted back to the oxidized enzyme byelectron transfer to azurin and elimination ... proton from the iminoquinoneintermediate formed in the reductive half-reaction of the catalytic cycle.Results Expression of recombinant AADHPlasmid pRKAADH was introduced via conjugationinto ... containingP. denitrificans.Characterization of recombinant AADHDuring the purification of recombinant AADH, the elution conditions during ion-exchange chromatogra-phy, hydrophobic interaction...
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Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

... exposure and positioning of the Tyr304 residue for binding to tyrosine kinases and phos-phatases. On the other hand, tyrosine phosphorylations donot affect the conformation of the PDZ binding motif ... within the SH2-binding element of eph-rinB2(301–333). On the other hand, tyrosine phosphorylation appears tohave a profound effect on the b-hairpin conformation of the SH2-binding region. First, ... tyrosine phosphorylations on the binding affinityof ephrinB2(301–333) to the SH2 domain of Grb4 and to the PDZdomain of PDZ-RGS3. In the combination experiments, the two Cterminal tyrosine residues...
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Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc

... aDNA fragment containing the Gmlbc3 promoter, the gusA gene, and the pAnos termination sequence bydigestion with HindIII; the digestion was followed by self-ligation of the remaining vector to ... responsiblefor intestinal absorption of vitamin B12facilitating itsinternalization [2,3,5]. Lack or malfunction of this Cblbinder hampers the uptake of the minute amounts of the vitamin present in food. ... periodical shaking.Then, the suspension was placed on ice for 1 h, whichstabilizes the thermo-labile bond between the cobalt atom ofCbl and the amino group. At that point the matrix can beeither used...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx

... represented in it. The system merely made no distinction between "all" and "any", and interpreted the final query to mean the But, you are probably thinking, those examples don't ... "yield" is ambiguous if there is both financial and productivity data in the knowledge base), and other complex linguistic phenomena. Let us go on to define the other end of the spectrum I began ... semester."), and other not-yet-mined-out topics. Extending the notion of database access to one of knowledge-base access where information may be manipulated in more complex ways, it is easy to generate...
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Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx

Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx

... through the serum stopper into eachflask with a syringe, and the flasks were then shaken gentlyfor 24 h at room temperature. The filters were thenremoved and placed into scintillation vials containing ... role in the maintenance of cell survival, but is alsoresponsible for the up-regulation of glucose metabo-lism and the induction of lipogenesis [37–40]. Wehypothesized that signaling via the ... production. The formation and maintenanceof LDs are complex, dynamic and highly regulatedprocesses [15,16]. The formation of LDs induced by NPs could be par-tially explained by a reduction in fat...
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Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx

Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx

... provide information on the localrepartition of the angles involved in the SREfoshelixbending.Relative effect of bending strainThere are several indications of a redistribution of the strains ... core-SRFmonomer could establish or not, some links with the second half-site. The main difference between SREfos and SREGfos, on the one hand, and SREGGfos, on the other hand,consists in the ... distinct strains acting on the helix ply ofthese oligonucleotides. Conversion between the bent and linear forms depends on local SRE constraints. Adecrease in the strains should freeze some conversionand...
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Báo cáo khoa học: Origins of DNA replication in the three domains of life pdf

Báo cáo khoa học: Origins of DNA replication in the three domains of life pdf

... manifested alongclassical evolutionary lines, with distinct combinations of replicon architec-ture and replication proteins being found in the three domains of life: the Bacteria, the Eukarya and the ... and C-terminal DNAbinding domains (DBDs). In DnaA, the DBD containsa helix-turn-helix; in the archaeal proteins, the DBDhas a winged helix domain (reviewed in [62]). Interest-ingly, the relative ... involved in the MCM assembly in buddingyeast [26]. The formation and activation of the pre-RCis crucial to the regulation of replication, ensuring thatany potential origin can only fire once per...
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Báo cáo khoa học:

Báo cáo khoa học: "PARSING VS. TEXT PROCESSING IN THE ANALYSIS OF DICTIONARY DEFINITIONS" pot

... verb definition texts begin with to followed by a head verb, or a set of conjoined head verbs. The most common words in the second position in inwansitive verb definitions, along with their ... feet The remaining failures resulted from errors in the creation of the tagged vocabulary (5), non-definitien dictionary lines incorrectly labeled as definition texts (53, and non-noun definitions ... but also (and primarily) to generate relational triples linking defined words to the major words used in their definitions. The large definition grammar is described more fully in Ahlswede...
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