Báo cáo khoa học: Molecular mechanisms in successful peripheral regeneration pot

... protein p311, also promote regeneration in injured motor nerves, resulting in accelerated reinnervation of peri- pheral targets [36]. Conversely, not every cyclin- dependent kinase inhibits regeneration. ... GTPase-activating protein 2 [143]. Axonal injury results in a small up-regulation of rhoA, rac, cdc42, and a massive increase in TC10 [144]. Inhibition of rhoA in vivo trigge...

Ngày tải lên: 30/03/2014, 16:20

... extracellular signal-regulated kinases (ERKs), the serine ⁄ threonine protein kinases belonging to the family of mitogen- activated protein kinases in cardiac myocytes [9]. ERKs play an important role in the downstream ... mito- gen-activated protein kinase pathway is involved in a number of cellular changes inducing growth and differ- entiation in human Schwann cells [7]. In cardia...

Ngày tải lên: 16/03/2014, 14:20

... transformation. In particular, the heat-induced dimerization does not occur via an unfolding–folding process. Finally, the CD measurements of the disulfide- containing variant indicate that the ... sequencing. Protein expression Plasmids were transformed into E. coli strain BL21(DE3) via electroporation, and grown overnight in 100 mL of LB medium containing 100 lgÆmL )1 ampicillin. Large-s...

Ngày tải lên: 06/03/2014, 11:20

... colony-stimulating factor [80], interleukin-2 and interferon-c [81]. The ARE-con- taining cytokine mRNAs interact with AUF1 factors, and this interaction targets them for degradation. Pin1 interferes ... its catalytic domain could induce structural changes in the N-terminal proline-rich domain of IRF-4. In the same field of immunology, Pin1 also regulates the production of such proinflammat...

Ngày tải lên: 07/03/2014, 05:20

... of interest for any rational user. All dominant options represent some tradeoff, but depending on the user’s interest, some of them are more interest- ing tradeoffs than others. Pruning dominated ... issue of giving the user a good overview of the option space, despite select- ing only the relevant options, by briefly accounting for the remaining (irrelevant) options. In the remainder of thi...

Ngày tải lên: 22/02/2014, 02:20

... Past Tapanainen and Atro Voutilainen. Compil- ing and using finite-state syntactic rules. In Pro- ceedings of the fifteenth International Conference on Computational Linguistics. COLING-92. Vol. ... FinVerbChain, FinAux NonFinMainVerb qUESTION; It reads: 'A finite clause subject (a constant de- fined as a regular expression elsewhere in the gram- mar) occurs before a finite v...

Ngày tải lên: 22/02/2014, 10:20

... the indefinite descrip- tions appearing in PDRSs, is to make them accessible in the main DRS. This paper shows, by slightly mod- ifying Klein's PDRSs, how that can be done, without losing ... slightly changing Klein's treatment of Predicate- DRSs, that is making indefinite descriptions occur- ring in the scope of the VP accessible to the top level of the main DRS, we obt...

Ngày tải lên: 22/02/2014, 10:20

... > 3 in order to incorporate global context is problematic as the tag sequences corresponding to higher order models will become increasingly rare in training data, leading to incorrect esti- mations ... with global contextual information, without making the model infeasible, by incor- porating the context separately from the POS tags. The new information incor- porated in the model i...

Ngày tải lên: 17/03/2014, 06:20

... constrains the mapping from variables in the lexical string to truth-values in the surface string, ensuring that whatever value is as- signed to x in one occurrence must be assigned to x in every ... BIGMA- CHINE, since interactions constrain the set of reachable state-combinations. Finally, it is worth considering whether the nondeter- minism involved in constructing the lex...

Ngày tải lên: 17/03/2014, 20:20

... system is to extend the types of training which the student gets in a class room setting into a computer. One important kind of training is the practising of dialogues. Therefore the program ... Proceedings of EACL '99 Dialogue Processing in a CALL-System Veit Reuer Institut fiir deutsche Sprache und Linguistik Humboldt-Universitgt zu Berlin Unter den Linden 6 10099 Berlin...

Ngày tải lên: 17/03/2014, 23:20