Báo cáo khoa học: Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation potx

... FEBS 1615 S. Ziegler et al. Wnt target genes and the regulation of their promoters Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation Slava Ziegler 1 , ... 5). Analysis of promoter regulation by Wnt signalling We screened databases for the promoters of the 15 genes that we had further a...

Ngày tải lên: 30/03/2014, 16:20

... represents the tilt of the major magnetic axis, z, away from the heme normal (z¢ axis), a is the angle between the projection of the tilt of the z axis on the x¢,y¢ plane (defined direction of tilt of ... ligated water molecule. The two structures of WT metHb and rWT metHbH 2 O, exhibit significant differences in the interaction of the FG loop with the he...

Ngày tải lên: 23/03/2014, 17:22

... segregated into COP II vesicles at the exit site from ER and therefore the mutant protein remains longer in the lumen of the ER and finally is diverted to the degradation pathway. Because the degradation ... [16–18]. According to the recommended nomenclature, the adenine of the initiator ATG codon in the cDNA of TNSALP is denoted as nucleotide +1 instead of...

Ngày tải lên: 19/02/2014, 17:20

... significant effect on the steroid output of the adrenal. The discovery that the two CYP17 isoforms are two genes and that the genotypes differ not only by the genes present, but also by the copy number, ... the target and reference genes. The PCR efficiencies were calculated from the slopes of the standard curves generated by light- cyclerÒ software (version...

Ngày tải lên: 07/03/2014, 06:20

... separated by the septum and the pulmonary artery valve is narrowed, causing a partial mixing of venal and arterial blood and a decrease of blood flow to the lungs. On the other hand, data from the source ... rather reflects synchrony to other events of the spermatogenesis. For instance, the mech- anisms unleashing the pass of the haploid germ cells through the...

Ngày tải lên: 16/03/2014, 23:20

... suggests the importance of the salt bridge interactions in the stabilization of the quater- nary structure and the importance of the salt composi- tion of the buffer to maintain the integrity of Arenicola ... intense, bands are also observed and they are present in all the other lanes in the mid- dle of the gel [17]. These bands have previously been repor...

Ngày tải lên: 23/03/2014, 10:21

... moie- ties of glycosphingolipids. On the basis of the presence of carbohydrate moieties of glycosphingolipids, we speculate about the potential involvement of a cera- mide glycanase in the catabolism of ... loss of 18 Da from the Z 1 ion. For the fragment ion with mass m ⁄ z 220.9, carbon chain cleavages at C 2 –C 3 and C 4 –C 5 of the aldohexonic acid were ass...

Ngày tải lên: 29/03/2014, 09:20

... as the degree and extent of branching and the relative abundance of a2 fi 3 and a2 fi 6 terminal sialic acids between cRBCs and HBEs, the present study provides insights into the inability of some human-adapted ... protons of GlcNAc, and the H3-equitorial and H3-axial protons of N-glycolylneuraminic acid [23–26]. The 1 H-NMR spectrum of cRBCs within the...

Ngày tải lên: 14/02/2014, 19:20

... presence of alternative splicing around the 5¢-end of exon 6 of Meis2 and Meis3 was tested by RT-PCR. The positions of molecular mass markers are shown to the left, and the size in base pairs of the ... 5¢-end of exon 6 of all three genes. In contrast, in the Prep1 gene, the equivalents of exons 5 and 6 in the Meis genes are present in a single exon. D...

Ngày tải lên: 16/02/2014, 15:20

... obtained with the transition at posi- tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant position and did not affect either of the other two ... of the wild-type 23S rRNA from the 50S and the 70S particles were similar: stop sites were found at positions 1911 and 1917 on the CMCT treated RNA and not on...

Ngày tải lên: 18/02/2014, 16:20