Báo cáo khoa học: Annexin A2 binds to the localization signal in the 3¢ untranslated region of c-myc mRNA ppt

... that annexin A2 binds to the 3¢UTR of c-myc mRNA and that the binding is to the defined section of the 3¢UTR B A Fig. 6. The binding of different c-myc transcripts to purified annexin A2. (A) Annexin A2 2 p11 2 heterotetramer ... that binding of annexin A2 to the localization signal in the c-myc mRNA leads to association with the...

Ngày tải lên: 30/03/2014, 15:20

... t M .As for t M , the intrinsic signal is faster than the extrinsic signal, however, the timing of the combined signal is between the intrinsic and the extrinsic signal, which results in S i <1. S K < ... extrin- sic signal. S i ¼ 1 shows that the extrinsic signal does not in uence the timing of the response to the intrinsic signal, but S e >...

Ngày tải lên: 30/03/2014, 10:20

... it is important to differentiate their detail level by adapting them to the user's competence in the domain. In our work, we want to study how to embed information obtained from a user ... exph'mation. THE CONSTRUCTION OF THE HYPOTHESES In the action identification phase a set of actions is selected from the plan library, each of them possibly r...

Ngày tải lên: 31/03/2014, 06:20

... leading to the preferential hydration of the protein domain is the driving force of protein stabiliza- tion or folding [3,4]. Furthermore, the effect of osmolytes on the functional activity of ... DG D ° values in the presence of these osmolytes are given in Table 1. How- ever, DG D ° values of RNase-A in the presence of alanine, serine, lysine, b-alanine,...

Ngày tải lên: 07/03/2014, 00:20

... demonstrated by changes in fluorescence. Furthermore, considering that inhibi- tion arises because inhibitors bound to the PAS hinder the entrance of acetylcholine to the CAS in the wild- type enzyme, ... lower efficiency of the alternative route compared to the main entrance, or to a partial overlap of the side chain of propidium and aflatoxin with the active...

Ngày tải lên: 07/03/2014, 05:20

... reduction; the use of the quinol-binding site inhibitor HOQNO shows that the inhibitor blocks binding of MQH 2 at the Q P site [27]. Study of the reduction and oxidation of the cytochrome has ... complicates the kinetic study of reduction of the cytochrome according to the choice of menadiol and duroquinol for spectral and kinetic studies. In uence of HOQN...

Ngày tải lên: 07/03/2014, 15:20

... that reinforces one of the meanings. For instance, gapping is felicitous in passage (3), where con- text supports the symmetric reading, but is infelicitous in passage (4) under the intended ... sections, we show how the distinct mecha- nisms for recovering these types of missing information interact with two types of discourse inference to predict the phenomena note...

Ngày tải lên: 08/03/2014, 07:20

... accompanied by an increase in the rate of synthesis of Ino, without any need to modify the kinetic parameters or activities of the enzymes involved in the pathway from ATP to Ino. Being aware of the simplifications ... concentration in a metabolic path- way as a function of the kinetic constants of the enzymes involved in that pathway [3]. Application of...

Ngày tải lên: 17/03/2014, 10:20

... generation. Results Accumulation of immature NCT in synoviolin-null cells To investigate whether Synoviolin is involved in the degradation of PS cofactors, we first compared the levels of PS cofactors by immunoblotting between synoviolin-null ... deletion of Synoviolin causes a change in the intracellular trafficking of NCT. Effect of Synoviolin on the production of...

Ngày tải lên: 23/03/2014, 04:20

... explained by the proximity of the mutation to the cleavage site, probably resulting in a small interference with the binding of the activator to the FXI zymogen. There are some examples of inherited ... activation loop at the N-terminus of the catalytic domain, are notable. In the zymogen FXI, Ile371 is exposed to the solvent, while in the activated F...

Ngày tải lên: 23/03/2014, 07:20