... that
annexin A2 binds to the 3¢UTR of c-myc mRNA and
that the binding is to the defined section of the 3¢UTR
B
A
Fig. 6. The binding of different c-myc transcripts to purified annexin
A2. (A) Annexin A2
2
p11
2
heterotetramer ... that binding of annexin A2
to the localization signal in the c-myc mRNA leads to association with the...
... t
M
.As
for t
M
, the intrinsic signal is faster than the extrinsic signal,
however, the timing of the combined signal is between the
intrinsic and the extrinsic signal, which results in S
i
<1.
S
K
< ... extrin-
sic signal. S
i
¼ 1 shows that the extrinsic signal does not
in uence the timing of the response to the intrinsic signal,
but S
e
>...
... it is important to differentiate
their detail level by adapting them to the user's
competence in the domain. In our work, we want to
study how to embed information obtained from a user ... exph'mation.
THE CONSTRUCTION OF THE
HYPOTHESES
In the action identification phase a set of actions is
selected from the plan library, each of them possibly
r...
... leading to the preferential hydration of the
protein domain is the driving force of protein stabiliza-
tion or folding [3,4]. Furthermore, the effect of
osmolytes on the functional activity of ... DG
D
° values in the
presence of these osmolytes are given in Table 1. How-
ever, DG
D
° values of RNase-A in the presence of
alanine, serine, lysine, b-alanine,...
... demonstrated by changes
in fluorescence. Furthermore, considering that inhibi-
tion arises because inhibitors bound to the PAS hinder
the entrance of acetylcholine to the CAS in the wild-
type enzyme, ... lower efficiency of the alternative route
compared to the main entrance, or to a partial overlap
of the side chain of propidium and aflatoxin with the
active...
... reduction; the use
of the quinol-binding site inhibitor HOQNO shows that the
inhibitor blocks binding of MQH
2
at the Q
P
site [27].
Study of the reduction and oxidation of the cytochrome
has ... complicates the kinetic
study of reduction of the cytochrome according to the
choice of menadiol and duroquinol for spectral and
kinetic studies.
In uence of HOQN...
... that reinforces one of the meanings. For
instance, gapping is felicitous in passage (3), where con-
text supports the symmetric reading, but is infelicitous
in passage (4) under the intended ... sections, we show how the distinct mecha-
nisms for recovering these types of missing information
interact with two types of discourse inference to predict
the phenomena note...
... accompanied by an increase in the rate of
synthesis of Ino, without any need to modify the kinetic
parameters or activities of the enzymes involved in the
pathway from ATP to Ino.
Being aware of the simplifications ... concentration in a metabolic path-
way as a function of the kinetic constants of the enzymes
involved in that pathway [3]. Application of...
... generation.
Results
Accumulation of immature NCT in synoviolin-null
cells
To investigate whether Synoviolin is involved in the
degradation of PS cofactors, we first compared the
levels of PS cofactors by immunoblotting between
synoviolin-null ... deletion of Synoviolin causes a change
in the intracellular trafficking of NCT.
Effect of Synoviolin on the production of...
... explained by the proximity of the
mutation to the cleavage site, probably resulting in a
small interference with the binding of the activator to
the FXI zymogen.
There are some examples of inherited ... activation loop at the N-terminus of the catalytic
domain, are notable. In the zymogen FXI, Ile371 is exposed to the
solvent, while in the activated F...