Báo cáo khoa học: Nucleocytoplasmic shuttling of STAT transcription factors Thomas Meyer and Uwe Vinkemeier doc

... MINIREVIEW Nucleocytoplasmic shuttling of STAT transcription factors Thomas Meyer and Uwe Vinkemeier Abteilung Zellula ¨ re Signalverarbeitung, Leibniz-Forschungsinstitut ... cells seven known STAT proteins were identified, den oted STAT1 , STAT2 , STAT3 , STAT4 , STAT5 a, S TAT5b, and STAT6 , all of which are activated by a distinct set of cytokines a nd gr...

Ngày tải lên: 30/03/2014, 15:20

... the understanding of molecular pathogenesis. Steady-state levels of Ab in brain and CSF, and the ratio between them in young transgenic mice are quite similar between the different models and conditions ... Transgenic mice are often bred on a mixed background, and complex genetics affects the steady-state level of Ab and Ab accumulation [138]. A difference in genetic backgroun...

Ngày tải lên: 16/02/2014, 09:20

... general transcription factors and co-activators, including general transcription fac- tor IIA (TFIIA) [31], Kin28 (a C-terminal-domain kinase of TFIIH) [32], the Taf9 subunit of TFIID and Spt-Ada-Gcn5 ... in the levels of HSF1 and MTA1 (a component of the NuRD complex containing HDAC1 and HDAC2) proteins and to binding of HSF1 to MTA1 [78]. The complex is recruited t...

Ngày tải lên: 18/02/2014, 04:20

... Peak 3 produced small amounts of HMG-CoA and large amounts of free CoA. Peak 4 produced HMG-CoA and also large amounts of free CoA. Peak 5 produced large amounts of HMG-CoA, but also free CoA. Human ... shoulder and the tailing is due to acetyl-CoA and not due to any other compound. (B) The peaks 3, 4, and 5 were isolated by HPLC and used as substrates for AUH. The AUH ass...

Ngày tải lên: 19/02/2014, 07:20

... modifier, noun, and a prepo- sitional joining term. We compare and evaluate different algorithms and different joining phrases on Nastase and Szpako- wicz’s (2003) dataset of 600 modifier-noun ... current state -of- the-art system; even with a relatively small set of prepositional join- ing terms. 1 Introduction Noun-modifier word pairs occur frequently in many languages, a...

Ngày tải lên: 20/02/2014, 12:20

... for Pta-F2 and Pta-F1. (B) Activation of the acetyl phosphate synthesis activity of E. coli Pta by different concentrations of pyruvate and PEP. Results are presented as percentage of activity ... 1961 Oligomeric state of Pta and the truncated Ptas The native oligomeric state of recombinant E. coli Pta was analyzed by size exclusion chromatography. With this technique, a nat...

Ngày tải lên: 06/03/2014, 11:20

... monomer and swapped dimer are mainly limited to the conformation of the Glu-Pro dipeptide in the hinge region between the last b-strand and the core of CKS. The crystal structure of the com- plex of ... proteo- lytic cleavage of the major pool of trans conformers [46,48]. The dephosphorylation of this pool of mainly cis conformers takes less time in the presence of Pin1...

Ngày tải lên: 07/03/2014, 05:20

... Arguments: Detection and Evaluation Sophia Katrenko Institute of Informatics University of Amsterdam the Netherlands katrenko@science.uva.nl Pieter Adriaans Institute of Informatics University of Amsterdam the ... positive and negative examples, one first builds the maximal canonical automaton (MCA) (Pernot et al., 2005) with one starting state and a separate sequence of states...

Ngày tải lên: 08/03/2014, 01:20

... Properties of the enzymatic steps/enzymes of the a-oxidation pathway. The table gives an overview of the present knowledge of some of the properties of the enzymes involved in the initial degradation of ... synthesis of phytol, geraniol, and nerol. Proceedings of the Chem. Soc. 263–264. 42. Ackman, R.G. & Hansen, R.P. (1967) The occurrence of dia- stereoisomers of...

Ngày tải lên: 08/03/2014, 02:20

... initiation and regulation of mouse ribonucleotide reductase R2 gene transcription Irina Kotova, Anna L. Chabes*, Sergei Lobov, Lars Thelander and Stefan Bjo¨ rklund Department of Medical Biochemistry and ... IIF, and IIH (reviewed in [1–3]). TFIID refers to a multiprotein complex composed of the TATA-binding protein (TBP) and a set of proteins called TBP-associated factor...

Ngày tải lên: 08/03/2014, 02:20