Báo cáo khoa học: Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs potx
Báo cáo khoa học: Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs potx
... Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs Keiichi Ishihara, Nobuyuki Yamagishi and Takumi Hatayama Department of Biochemistry, ... °C for 1 h and furt her incubated for 6 h , the cellular levels of Hsp105a and Hsc70 (a constitutive isoform of Hsp70) increased, and t he expression of Hsp70 (an inducibl...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo khoa học: Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1 pdf
... optimized by infecting Sf9 cells with different amounts of virus and by expression for various periods. Aliquots of the culture sup- ernatants and cell pellets were analyzed by SDS ⁄ PAGE and immunoblotting ... P2 1 2 1 2 1 and diffracted X-rays to a resolution of 2.9 A ˚ (Fig. 4). Phl p 1 and Phl p 2 belong to different clusters of proteins as determined by phylogen...
Ngày tải lên: 16/03/2014, 18:20
Tài liệu Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development pptx
... over-expres- sion of Hsp60 and Hsp70 and exhibit abnormal mor- phology in correlation with increased proliferation, premature differentiation and elongation, inhibition of denucleation and of loss of organelles ... (Tdag51) by direct HSF1 binding of a HSE in the proximal promoter region of the Tdag51 gene. Tdag51 is a member of the PHL domain family and its N-termina...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khóa học: Suppression of b1,3galactosyltransferase b3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans Lydia Mare and Marco Trinchera pdf
... discussion, and Prof. F. Dall’Olio (Department of Experimental Pathology, University of Bologna) for critical reading of the manuscript. This work was supported by grants from MIUR (COFIN 2001) and from ... oligosaccharides formed in BxPC3 cells (j in lower part, and A, B, and C of upper part) andT5ASclone(h in lower part, and A, B, and C of upper part) metabolically r...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Suppression of microtubule dynamics by benomyl decreases tension across kinetochore pairs and induces apoptosis in cancer cells potx
... 5 and 20 l M of benomyl treatment (lanes 2 and 3); and 40 h after 5 and 20 l M of benomyl treatment (lanes 4 and 5). Fig. 9. Benomyl induced hyperphosphorylation of bcl2 and dissoci- ation of ... Cleavage of PARP by benomyl treatment. HeLa cells were treated with the indi- cated concentrations of drugs for 40 h and equal amounts of cell lysates were resolved b...
Ngày tải lên: 30/03/2014, 10:20
Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
... 5767 MINIREVIEW Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction Abdulmaged M. Traish 1 , Robert J. Feeley 1 and Andre ... pathophysiological mechanisms of endothelial dysfunction and testosterone deficiency include penile vascular insufficiency as a result of the loss of nitr...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS ppt
... assigned as c¢ 38 +5 and z¢ Æ 67 +5 , respectively. Sequence coverage of Rev provided by ions of type c¢ and z¢ Æ is indicated by solid and dashed lines, respec- tively, above and below the sequence ... Fragmentation scheme for production of ions of type c¢ and z¢ Æ by reaction of a low-energy electron with a multiply protonated peptide. ETD-MS analysis of peptides...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Binding of N- and C-terminal anti-prion protein antibodies generates distinct phenotypes of cellular prion proteins (PrPC) obtained from human, sheep, cattle and mouse doc
... the protein bands were analyzed by calcula- tion of the percentages of the di- (d), mono- (j) and nonglycosy- lated (m) isoform as arithmetic means of separate gel runs. The number of gel runs ... nonglycosylated isoform (m) of PrP C were quantified and calcu- lated as percentages of the total signal. The glycoforms of the pro- tein bands were analyzed as arithmetic means...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... highlighted in green and the nitrogen atoms of R120 and K22 in blue. The open form of MurA is unliganded (A) and the closed conformation (B) contains fosfo- mycin (orange) and UDPNAG (purple) ... UDP-N-acetylmuramic acid) (A) and inactivation mechanism of MurA by fosfomycin as a result of the covalent linkage between Cys115 of MurA and fosfomycin (B). Ó FEBS 2004 Lysin...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: "Order of Subject and Predicate in Scientific Russia" pptx
... twenty-eight pages of continuous text 2 were analyzed for the relative positions of the subject and the predicate. The predicate spot was determined syntactically, by its func- tion, and the following ... " In support of this statement, Harper quotes certain figures: "From a sample of 1, 528 sentences containing a subject and verb: Subject before verb: 81...
Ngày tải lên: 19/02/2014, 19:20